Many countries continue to experience pertussis epidemics despite widespread vaccination.
Waning protection after booster vaccination has highlighted the need for a better …

As an emerging two-dimensional nanomaterial with promising prospects, mono-or few-layer
black phosphorus (BP) is potentially toxic to humans. We investigated the effects of two …

Whole cell vaccines are frequently the first generation of vaccines tested for pathogens and
can inform the design of subsequent acellular or subunit vaccines. For respiratory …

Acute pathogens such as Bordetella pertussis can cause severe disease but are ultimately
cleared by the immune response. This has led to the accepted paradigm that convalescent …

Abstract Background The Bacillus Calmette-Guérin (BCG), the only vaccine against
tuberculosis (TB) currently in use, has shown beneficial effects against unrelated infections …

Pertussis remains endemic in vaccinated populations due to waning of vaccine-induced
immunity and insufficient interruption of transmission. Correlates of long-term protection …

Brucella canis is a Gram-negative, facultative intracellular bacterium and the causative
agent of canine brucellosis, a highly contagious disease of dogs that can be transmitted to …

Over two decades ago acellular pertussis vaccines (aP) replaced whole cell pertussis
vaccines (wP) in several countries. Since then, a resurgence in pertussis has been …

Despite widespread vaccination, B. pertussis remains one of the least controlled vaccine-
preventable diseases. Although it is well known that acellular and whole cell pertussis …

The conduct of industrial pig breeding involves technological stresses that cause adaptive
changes in the body, requiring additional energyconsumption, which negatively affects the …