What are the benefits of a sustained virologic response to direct-acting antiviral therapy for hepatitis C virus infection?

GN Ioannou, JJ Feld - Gastroenterology, 2019 - Elsevier
Direct-acting antiviral (DAA) regimens are safe and effective at eradicating hepatitis C virus
(HCV) infection. Unfortunately, DAAs remain expensive, so treatment of all HCV-infected …

Natural history of acute and chronic hepatitis C

B Maasoumy, H Wedemeyer - Best practice & research Clinical …, 2012 - Elsevier
Hepatitis C virus (HCV) infection remains a major global health burden. Hepatitis C causes
significant liver-related morbidity and mortality due to hepatic decompensation and …

Hepatitis C infection and risk of diabetes: a systematic review and meta-analysis

DL White, V Ratziu, HB El-Serag - Journal of hepatology, 2008 - Elsevier
BACKGROUND/AIMS: Several studies found hepatitis C (HCV) increases risk of Type II
diabetes mellitus (DM). However, others found no or only sub-group specific excess risk. We …

[PDF][PDF] Antiviral treatment for hepatitis C virus infection is associated with improved renal and cardiovascular outcomes in diabetic patients

YC Hsu, JT Lin, HJ Ho, YH Kao, YT Huang… - …, 2014 - Wiley Online Library
Hepatitis C virus (HCV) infection is causally associated with insulin resistance and diabetes
mellitus. This population‐based cohort study aimed to investigate whether antiviral therapy …

Sustained virologic response to antiviral therapy for chronic hepatitis C virus infection: a cure and so much more

BL Pearlman, N Traub - Clinical infectious diseases, 2011 - academic.oup.com
Sustained virologic response (SVR) is defined as aviremia 24 weeks after completion of
antiviral therapy for chronic hepatitis C virus (HCV) infection. In analyses of SVR durability …

New onset diabetes after transplantation (NODAT): an overview

PTT Pham, PMT Pham, SV Pham… - … syndrome and obesity …, 2011 - Taylor & Francis
Although renal transplantation ameliorates cardiovascular risk factors by restoring renal
function, it introduces new cardiovascular risks including impaired glucose tolerance or …

Achieving sustained virologic response in hepatitis C: a systematic review of the clinical, economic and quality of life benefits

J Smith-Palmer, K Cerri, W Valentine - BMC infectious diseases, 2015 - Springer
Background The goal of chronic hepatitis C treatment is to remove the virus to avoid
progression of HCV-related disease. Sustained virologic response (SVR) is the most widely …

Improvement in glycemic control of type 2 diabetes after successful treatment of hepatitis C virus

J Hum, JH Jou, PK Green, K Berry, J Lundblad… - Diabetes …, 2017 - Am Diabetes Assoc
OBJECTIVE Hepatitis C virus (HCV) infection is associated with diabetes and may worsen
glycemic control in patients with diabetes. We aimed to investigate whether eradication of …

[HTML][HTML] Metabolic complications of hepatitis C virus infection

R Chaudhari, S Fouda, A Sainu… - World journal of …, 2021 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) infection is a systemic disease that is implicated in multiple
extrahepatic organ dysfunction contributing to its protean manifestations. HCV is associated …

[PDF][PDF] Sustained virological response reduces incidence of onset of type 2 diabetes in chronic hepatitis C

Y Arase, F Suzuki, Y Suzuki, N Akuta… - …, 2009 - Wiley Online Library
Diabetes is present in patients with chronic hepatitis C virus infection. The aim of this
retrospective cohort study was to assess the cumulative development incidence and …