Microbubble agents: New directions

E Stride, T Segers, G Lajoinie, S Cherkaoui… - Ultrasound in medicine …, 2020 - Elsevier
Microbubble ultrasound contrast agents have now been in use for several decades and their
safety and efficacy in a wide range of diagnostic applications have been well established …

Therapeutic oxygen delivery by perfluorocarbon-based colloids

MP Krafft, JG Riess - Advances in colloid and interface science, 2021 - Elsevier
After the protocol-related indecisive clinical trial of Oxygent, a perfluorooctylbromide/
phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned the observed …

[HTML][HTML] A laser-activated biocompatible theranostic nanoagent for targeted multimodal imaging and photothermal therapy

L Deng, X Cai, D Sheng, Y Yang, EM Strohm… - Theranostics, 2017 - ncbi.nlm.nih.gov
Multifunctional nanoparticles have been reported for cancer detection and treatment
currently. However, the accurate diagnosis and efficient treatment for tumors are still not …

Methods of generating submicrometer phase-shift perfluorocarbon droplets for applications in medical ultrasonography

PS Sheeran, N Matsuura, MA Borden… - IEEE transactions on …, 2016 - ieeexplore.ieee.org
Continued advances in the field of ultrasound and ultrasound contrast agents have created
new approaches to imaging and medical intervention. Phase-shift perfluorocarbon droplets …

Engineering intelligent nanosystems for enhanced medical imaging

GT van Moolenbroek, T Patiño, J Llop… - Advanced Intelligent …, 2020 - Wiley Online Library
Medical imaging serves to obtain anatomical and physiological data, supporting medical
diagnostics as well as providing therapeutic evaluation and guidance. A variety of contrast …

Synthesis of stable multifunctional perfluorocarbon nanoemulsions for cancer therapy and imaging

DA Fernandes, DD Fernandes, Y Li, Y Wang, Z Zhang… - Langmuir, 2016 - ACS Publications
Nanotechnology provides a promising platform for drug-delivery in medicine.
Nanostructured materials can be designed with desired superparamagnetic or fluorescent …

Factors influencing the repeated transient optical droplet vaporization threshold and lifetimes of phase change, perfluorocarbon nanodroplets

AX Zhao, YI Zhu, E Chung, J Lee, S Morais, H Yoon… - Nanomaterials, 2023 - mdpi.com
Perfluorocarbon nanodroplets (PFCnDs) are sub-micrometer emulsions composed of a
surfactant-encased perfluorocarbon (PFC) liquid and can be formulated to transiently …

On the thermodynamics and kinetics of superheated fluorocarbon phase-change agents

PA Mountford, MA Borden - Advances in colloid and interface science, 2016 - Elsevier
Superheated nanodrops are a new class of submicron-diameter liquid emulsion particles
comprising perfluoropropane (C 3 F 8), perfluorobutane (C 4 F 10) and perfluoropentane (C …

Spontaneous nucleation of stable perfluorocarbon emulsions for ultrasound contrast agents

DS Li, S Schneewind, M Bruce, Z Khaing… - Nano …, 2018 - ACS Publications
Phase-change contrast agents are rapidly developing as an alternative to microbubbles for
ultrasound imaging and therapy. These agents are synthesized and delivered as liquid …

Thermal activation of superheated lipid-coated perfluorocarbon drops

PA Mountford, AN Thomas, MA Borden - Langmuir, 2015 - ACS Publications
This study explored the thermal conditions necessary for the vaporization of superheated
perfluorocarbon nanodrops. Droplets C3F8 and C4F10 coated with a homologous series of …