Arginine signaling and cancer metabolism

CL Chen, SC Hsu, DK Ann, Y Yen, HJ Kung - Cancers, 2021 - mdpi.com
Simple Summary In this review, we describe arginine's role as a signaling metabolite,
epigenetic regulator and mitochondrial modulator in cancer cells, and summarize recent …

Endocrine role of bone in the regulation of energy metabolism

R Zhou, Q Guo, Y Xiao, Q Guo, Y Huang, C Li, X Luo - Bone research, 2021 - nature.com
Abstracts Bone mainly functions as a supportive framework for the whole body and is the
major regulator of calcium homeostasis and hematopoietic function. Recently, an increasing …

Membrane-initiated estrogen, androgen, and progesterone receptor signaling in health and disease

F Mauvais-Jarvis, CA Lange, ER Levin - Endocrine reviews, 2022 - academic.oup.com
Rapid effects of steroid hormones were discovered in the early 1950s, but the subject was
dominated in the 1970s by discoveries of estradiol and progesterone stimulating protein …

Role of nutrient-sensing receptor GPRC6A in regulating colonic group 3 innate lymphoid cells and inflamed mucosal healing

Q Hou, J Huang, X Xiong, Y Guo… - Journal of Crohn's and …, 2022 - academic.oup.com
Abstract Background and Aims Group 3 innate lymphoid cells [ILC3s] sense environmental
signals and are critical in gut homeostasis and immune defence. G-protein-coupled …

Quercetin Attenuates Osteoporosis in Orchiectomy Mice by Regulating Glucose and Lipid Metabolism via the GPRC6A/AMPK/mTOR Signaling Pathway

J Sun, Y Pan, X Li, L Wang, M Liu, P Tu, C Wu… - Frontiers in …, 2022 - frontiersin.org
Quercetin, a flavonoid found in natural medicines, has shown a role in disease prevention
and health promotion. Moreover, because of its recently identified contribution in regulating …

Endocrine disruptors and prostate cancer

M Corti, S Lorenzetti, A Ubaldi, R Zilli… - International Journal of …, 2022 - mdpi.com
The role of endocrine disruptors (EDs) in the human prostate gland is an overlooked issue
even though the prostate is essential for male fertility. From experimental models, it is known …

A review on the role of food-derived bioactive molecules and the microbiota–gut–brain axis in satiety regulation

NA Pizarroso, P Fuciños, C Gonçalves, L Pastrana… - Nutrients, 2021 - mdpi.com
Obesity is a chronic disease resulting from an imbalance between energy intake and
expenditure. The growing relevance of this metabolic disease lies in its association with …

Vascular mechanisms of testosterone: the non-genomic point of view

M Lorigo, M Mariana, MC Lemos, E Cairrao - The Journal of steroid …, 2020 - Elsevier
Testosterone (T) is the predominant endogenous androgen in the bloodstream. At the
vascular level, T presents genomic and non-genomic effects, and both effects may overlap …

Molecular characterization of membrane steroid receptors in hormone-sensitive cancers

M Masi, M Racchi, C Travelli, E Corsini, E Buoso - Cells, 2021 - mdpi.com
Cancer is one of the most common causes of death worldwide, and its development is a
result of the complex interaction of genetic factors, environmental cues, and aging. Hormone …

Potential role for osteocalcin in the development of atherosclerosis and blood vessel disease

A Tacey, T Qaradakhi, T Brennan-Speranza, A Hayes… - Nutrients, 2018 - mdpi.com
There is increasing evidence for the involvement of the skeleton in the regulation of
atherosclerotic vascular disease. Osteocalcin, an osteoblast derived protein, exists in two …