Endothelial cells (ECs) are vascular, nonconventional immune cells that play a major role in
the systemic response after bacterial infection to limit its dissemination. Triggered by …

Sepsis is a deadly inflammatory syndrome caused by an exaggerated immune response to
infection. Much has been focused on host response to pathogens mediated through the …

Multiple organ dysfunction is the most severe outcome of sepsis progression and is highly
correlated with a worse prognosis. Excessive neutrophil extracellular traps (NETs) are …

This retrospective study was designed to explore whether neutrophil to lymphocyte ratio
(NLR) is a prognostic factor in patients with coronavirus disease 2019 (COVID‐19). A cohort …

Fracture-related infection (FRI) is a severe complication after bone injury and can pose a
serious diagnostic challenge. Overall, there is a limited amount of scientific evidence …

Acute inflammation is essential for initiating and coordinating the body's response to injuries
and infections. However, in acute inflammatory diseases, inflammation is not resolved but …

There is growing recognition of the critical role of platelets in inflammation and immune
responses. Recent studies have indicated that antiplatelet medications may reduce mortality …

Objectives To assess the utility of the neutrophil: lymphocyte (NLR), lymphocyte: monocyte
(LMR) and platelet: lymphocyte ratios (PLR) as infection biomarkers. Methods …

Sepsis is characterized by a dysregulated immune response to infections that causes life-
threatening organ dysfunction and even death. When infections occur, bacterial cell wall …

Sepsis is considered a major public health problem. Despite mortality being associated
consistently with organ compromise, the mechanisms by which sepsis causes multiple …