The long-term survival of any multicellular species depends on the success of its germline in
producing high-quality gametes and maximizing survival of the offspring. Studies in …

Background The formation of matured and individual sperm involves a series of molecular
and spectacular morphological changes of the developing cysts in Drosophila melanogaster …

Phagoptosis is a frequently occurring nonautonomous cell death pathway in which
phagocytes eliminate viable cells. While it is thought that phosphatidylserine (PS)“eat-me” …

Codon usage bias has long been appreciated to influence protein production. Yet, relatively
few studies have analyzed the impacts of codon usage on tissue-specific mRNA and protein …

Cellular trafficking through the endosomal–lysosomal system is essential for the transport of
cargo proteins, receptors and lipids from the plasma membrane inside the cells and across …

BACKGROUND Protein kinases are a type of transferase enzyme that catalyze the
phosphorylation of protein substrates, including receptor proteins. Testis‐specific …

The spermatogenesis of animal is essential for the reproduction and a very large number of
genes participate in this procession. The Maelstrom (Mael) is identified essential for …

In all metazoan species, sperm is produced from germline stem cells. These self-renew and
produce daughter cells that amplify and differentiate dependent on interactions with somatic …

Drosophila male germline stem cells (GSCs) reside at the tip of the testis and surround a
cluster of niche cells. Decapentaplegic (Dpp) is one of the well-established ligands and has …

One fundamental property of a stem cell niche is the exchange of molecular signals between
its component cells. Niche models, such as the Drosophila melanogaster testis, have been …