Background: Colorectal cancer (CRC) follows a protracted stepwise progression, from
benign adenomas to malignant adenocarcinomas. If detected early, 90% of deaths are …

While great strides in improving survival rates have been made for most cancers in recent
years, pancreatic ductal adenocarcinoma (PDAC) remains one of the solid tumors with the …

Pancreatic ductal adenocarcinoma (PDAC) originates from normal pancreatic ducts where
digestive juice is regularly produced. It remains unclear how PDAC can escape …

Background Pancreatic adenocarcinoma (PAAD) is among the most lethal diseases and has
a dismal prognosis; however, efficient treatment is currently limited. Several studies have …

Background & Aims Recent pancreatic cancer surveillance programs of high-risk individuals
have reported improved outcomes. This study assessed to what extent outcomes of …

Abstract Background Objectives: Pancreatic cysts are frequently detected in high-risk
individuals (HRI) undergoing surveillance for pancreatic cancer. The International Cancer of …

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal
cancers, and developing an efficient and reliable approach for its early-stage diagnosis is …

Purpose: We have previously identified tissue methylated DNA markers (MDMs) associated
with pancreatic ductal adenocarcinoma (PDAC). In this case–control study, we aimed to …

Introduction Most patients with pancreatic cancer present with advanced stage, incurable
disease. However, patients with high-grade precancerous lesions and many patients with …

Background Engulfment and cell motility protein 1 (ELMO1) is a key protein for innate
immunity since it is required for the clearance of apoptotic cells and pathogenic bacteria as …