Eukaryotic cells require sufficient oxygen (O2) for biological activity and survival. When the
oxygen demand exceeds its supply, the oxygen levels in local tissues or the whole body …

In this paper, we conduct theoretical analyses on inferring the structure of gene regulatory
networks. Depending on the experimental method and data type, the inference problem is …

Abstract Cassava (Manihot esculenta Crantz) is a major world crop, whose storage roots
provide food for over 800 million throughout the humid tropics. Despite many advantages as …

Chronic myeloid leukemia (CML) is potentially fatal blood cancer, but there is an unmet
need to discover novel molecular biomarkers. The hypothesis of this study aimed to …

Virally mediated RNA interference (RNAi) to knock down injury-induced genes could
improve functional outcome after traumatic brain injury (TBI); however, little is known about …

Abstract The RNA-guided CRISPR/Cas9 system has been shown to be a powerful tool for
genome editing in various organisms. A comprehensive toolbox for multiplex genome …

One of the most fundamental molecular processes in response to hypoxia is the activation
and stabilization of a transcriptional factor called hypoxia induced factor 1a (HIF-1a), which …

Lignans are diphenolic compounds produced in plants via coupling of two coniferyl alcohol
molecules with the aid of a dirigent protein to form pinoresinol (PINO). The latter is reduced …

La neoplasia endocrina múltiple de tipo 1 (MEN-1) es una enfermedad que puede dar lugar
a la formación de cáncer en células y tejidos del sistema endocrino (Khatami y Tavagnar …

Although numerous studies containing induced gene expression have already been
published, independent authentication of their results has not yet been performed. Here, we …