Multiple Mutations on α, β and γ Domains of Streptokinase Lead to the Generation of Highly Efficient Cysteine Analogues with Promising Features

NN Alinodehi, H Behrooz, M Sabaei… - Current …, 2023 - ingentaconnect.com
Background: Streptokinase, one of the most widely used thrombolytic medicines, is a
favorable protein for site-specific PEGylation as it lacks any cysteine residues in its amino …