Promising anti-inflammatory effects of chalcones via inhibition of cyclooxygenase, prostaglandin E2, inducible NO synthase and nuclear factor κb activities

H ur Rashid, Y Xu, N Ahmad, Y Muhammad… - Bioorganic Chemistry, 2019 - Elsevier
Abstract Chalcones (1, 3-Diphenyl-2-propen-1-one) consist of a three carbon α, β-
unsaturated carbonyl system and act as precursors for the biosynthesis of flavonoids in …

[HTML][HTML] Biological activities of Chromolaena odorata: A mechanistic review

F Olawale, K Olofinsan, O Iwaloye - South African Journal of Botany, 2022 - Elsevier
Chromolaena odorata is a perennial shrub that grows abundantly in Asia and sub-Saharan
Africa, where it has been used in the treatment of many ailments and disease conditions …

Synthesis and biological evaluation of chalcone-polyamine conjugates as novel vectorized agents in colorectal and prostate cancer chemotherapy

B Rioux, A Pinon, A Gamond, F Martin… - European journal of …, 2021 - Elsevier
The aim of this study was to synthesize chalcone-polyamine conjugates in order to enhance
bioavailability and selectivity of chalcone core towards cancer cells, using polyamine-based …

Anti-inflammatory activity of extracts and pure compounds derived from plants via modulation of signaling pathways, especially PI3K/AKT in macrophages

A Merecz-Sadowska, P Sitarek, T Śliwiński… - International journal of …, 2020 - mdpi.com
The plant kingdom is a source of important therapeutic agents. Therefore, in this review, we
focus on natural compounds that exhibit efficient anti-inflammatory activity via modulation …

Chalcones: A review on synthesis and pharmacological activities

K Goyal, R Kaur, A Goyal, R Awasthi - Journal of Applied …, 2021 - japsonline.com
Chalcone is a privileged species with medicinal significance as it consists of reactive
ketoethylenic moiety–CO–CH= CH–belonging to flavonoids. The presence of a reactive α, β …

A Novel Tri-Hydroxy-Methylated Chalcone Isolated from Chromolaena tacotana with Anti-Cancer Potential Targeting Pro-Survival Proteins

G Mendez-Callejas, M Piñeros-Avila… - International Journal of …, 2023 - mdpi.com
Chromolaena tacotana (Klatt) RM King and H. Rob (Ch. tacotana) contains bioactive
flavonoids that may have antioxidant and/or anti-cancer properties. This study investigated …

A review of chalcones: synthesis, reactions, and biological importance

SS Mukhtar, NM Morsy, AS Hassan… - Egyptian Journal of …, 2022 - ejchem.journals.ekb.eg
Chalcones are considered an important scaffold in organic compounds. Many of their
derivatives have a lot of applications. Therefore, this review was covered some synthesis …

Improved curcumin recovery and in vitro biological activity of turmeric extracts using nipa palm syrup–and nipa palm vinegar–based Natural Deep Eutectic Solvent …

T Rodsamai, M Chaijan, M Nisoa, N Donlao… - Food and Bioprocess …, 2024 - Springer
This was the first study to use local Southern Thai ingredients, namely, nipa palm syrup (NS)
and nipa palm vinegar (NV), in the formulation of natural deep eutectic solvent (NADES) for …

Natural 2′,4-Dihydroxy-4′,6′-dimethoxy Chalcone Isolated from Chromolaena tacotana Inhibits Breast Cancer Cell Growth through Autophagy and Mitochondrial …

G Mendez-Callejas, M Piñeros-Avila, CA Celis… - Plants, 2024 - mdpi.com
Breast cancer (BC) is one of the most common cancers among women. Effective treatment
requires precise tailoring to the genetic makeup of the cancer for improved efficacy …

Systematic Review: Efektivitas Ekstrak Daun Kirinyuh (Chromolaena Odorata L.) Terhadap Penyembuhan Luka Studi In Vivo Dan In Vitro

BO Putry, E Harfiani, YS Tjang - Seminar Nasional Riset …, 2021 - conference.upnvj.ac.id
Luka merupakan kondisi dimana terjadi kerusakan jaringan akibat terputusnya kontinuitas
jaringan. Tinggi nya insidensi luka menyebabkan perlunya ditemukan penatalaksanaan …