Role of the microbiome in gut-heart-kidney cross talk
G Glorieux, SK Nigam, R Vanholder… - Circulation …, 2023 - Am Heart Assoc
Homeostasis is a prerequisite for health. When homeostasis becomes disrupted, dysfunction
occurs. This is especially the case for the gut microbiota, which under normal conditions …
occurs. This is especially the case for the gut microbiota, which under normal conditions …
[HTML][HTML] In Vivo Regulation of Small Molecule Natural Products, Antioxidants, and Nutrients by OAT1 and OAT3
K Falah, P Zhang, AK Nigam, K Maity, G Chang… - Nutrients, 2024 - mdpi.com
The organic anion transporters OAT1 (SLC22A6) and OAT3 (SLC22A8) are drug
transporters that are expressed in the kidney, with well-established roles in the in vivo …
transporters that are expressed in the kidney, with well-established roles in the in vivo …
New Biomarkers for Renal Transporter‐Mediated Drug–Drug Interactions: Metabolomic Effects of Cimetidine, Probenecid, Verapamil, and Rifampin in Humans
The inhibition of renal transport proteins organic cation transporter 2 (OCT2), multidrug and
toxin extrusion proteins (MATE1, MATE2‐K), and organic anion transporters (OAT1, OAT3) …
toxin extrusion proteins (MATE1, MATE2‐K), and organic anion transporters (OAT1, OAT3) …
Proximal tubule-on-chip as a model for predicting cation transport and drug transporter dynamics
I Petit, Q Faucher, JS Bernard, P Giunchi, A Humeau… - Scientific Reports, 2025 - nature.com
Deciphering the sources of variability in drug responses requires to understand the
processes modulating drug pharmacokinetics. However, pharmacological research suffers …
processes modulating drug pharmacokinetics. However, pharmacological research suffers …
Genome-wide association study reveals shared and distinct genetic architecture of fatty acids and oxylipins in the Hispanic Community Health Study/Study of Latinos
Bioactive fatty acid-derived oxylipin molecules play key roles mediating inflammation and
oxidative stress. Circulating levels of fatty acids and oxylipins are influenced by …
oxidative stress. Circulating levels of fatty acids and oxylipins are influenced by …
Genome-wide association study reveals shared and distinct genetic architecture underlying fatty acid and bioactive oxylipin metabolites in the Hispanic Community …
Bioactive fatty acid-derived oxylipin molecules play key roles in mediating inflammation and
oxidative stress, which underlie many chronic diseases. Circulating levels of fatty acids and …
oxidative stress, which underlie many chronic diseases. Circulating levels of fatty acids and …
Inflammatory Mediators of Type 2 Diabetes Risk
CG Downie - 2023 - search.proquest.com
Inflammation is a pathological feature underlying many chronic diseases, including type 2
diabetes (T2D). Inflammatory mediators include both signaling proteins (eg, cytokines) and …
diabetes (T2D). Inflammatory mediators include both signaling proteins (eg, cytokines) and …