Cells sense and respond to the biochemical and physical properties of the extracellular
matrix (ECM) through adhesive structures that bridge the cell cytoskeleton and the …

Endocytosis is a mechanosensitive process. It involves remodeling of the plasma membrane
from a flat shape to a budded morphology, often at the sub‐micrometer scale. This …

Aims Anti-angiotherapy (Bevacizumab) is currently regarded as a promising option for
glioma patients who are resistant to temozolomide (TMZ) treatment. But ongoing clinical …

The formation of bone in a bone defect is accomplished by osteoblasts, while the over
activation of fibroblasts promotes fibrosis. However, it is not clear how the extracellular …

In egress routes of malignancy, cancer cells are constantly subjected to shear stress
imposed by blood/lymph flow. Increasing evidence points toward the regulatory roles of …

The therapy for breast cancer (BC), to date, still needs improvement. Apart from traditional
therapy methods, biological therapy being explored opens up a novel avenue for BC …

Cells are subjected to multiple mechanical inputs throughout their lives. Their ability to
detect these environmental cues is called mechanosensing, a process in which integrins …

目的研究ITGA5 经RNA 干扰后对宫颈癌细胞生长和侵袭的影响. 方法应用TNMplot, Kaplan-
Meier Plotter, Human Protein Atlas 数据库分析ITGA5 在宫颈癌中的表达和对患者生存率的 …

The incidence of diabetic patients with non-alcoholic fatty liver disease (NAFLD) is
continuously increasing worldwide. However, the specific mechanisms of NAFLD patients …

In this study, we investigated the effects of extracellular matrix rigidity, an important physical
property of microenvironments regulating cell morphology and functions, on sonoporation …