Cold-inducible proteins CIRP and RBM3, a unique couple with activities far beyond the cold

X Zhu, C Bührer, S Wellmann - Cellular and molecular life sciences, 2016 - Springer
Cold-inducible RNA-binding protein (CIRP) and RNA-binding motif protein 3 (RBM3) are
two evolutionarily conserved RNA-binding proteins that are transcriptionally upregulated in …

RNA binding proteins in intestinal epithelial biology and colorectal cancer

P Chatterji, AK Rustgi - Trends in molecular medicine, 2018 - cell.com
The intestinal epithelium is highly proliferative and consists of crypt invaginations that house
stem cells and villus projections with differentiated cells. There exists a dynamic equilibrium …

Alternative polyadenylation: another foe in cancer

AE Erson-Bensan, T Can - Molecular Cancer Research, 2016 - AACR
Advancements in sequencing and transcriptome analysis methods have led to seminal
discoveries that have begun to unravel the complexity of cancer. These studies are paving …

RBM3 is an outstanding cold shock protein with multiple physiological functions beyond hypothermia

Y Hu, Y Liu, X Quan, W Fan, B Xu… - Journal of Cellular …, 2022 - Wiley Online Library
RNA‐binding motif protein 3 (RBM3), an outstanding cold shock protein, is rapidly
upregulated to ensure homeostasis and survival in a cold environment, which is an …

Alternative splicing by NOVA factors: from gene expression to cell physiology and pathology

J Meldolesi - International Journal of Molecular Sciences, 2020 - mdpi.com
NOVA1 and NOVA2, the two members of the NOVA family of alternative splicing factors, bind
YCAY clusters of pre-mRNAs and assemble spliceosomes to induce the …

PCBP2 Posttranscriptional Modifications Induce Breast Cancer Progression via Upregulation of UFD1 and NT5E

X Wang, Q Guo, H Wang, X Yuan, B Wang… - Molecular Cancer …, 2021 - AACR
It is commonly accepted that cellular protein levels are primarily determined by mRNA
levels. However, discordance between protein and mRNA expression has been implicated …

Transcriptomic changes in brain development

AA Dillman, MR Cookson - International review of neurobiology, 2014 - Elsevier
The transcriptome changes hugely during development of the brain. Whole genes, alternate
exons, and single base pair changes related to RNA editing all show differences between …

Computational methods to identify and characterize the functionality of polyadenylation isoforms

D Burri - 2023 - edoc.unibas.ch
Polyadenylation is the process by which poly (A) tails are added at the 3'end of an RNA
molecule. Alternative polyadenylation (APA) can occur when multiple poly (A) sites exist …

Noncanonical human eIF4Es in and out of the RNA granules

K Frydrýšková - 2020 - dspace.cuni.cz
Eukaryotic translation initiation factor eIF4E1 (eIF4E1) plays a pivotal role in the control of
cap-dependent translation initiation, occurs in P-bodies and is important for the formation of …

Dynamic basis of mRNA processing in male germline stem cell pluripotency and reprogramming by alternative polyadenylation

PK Guttula, MK Gupta - International Journal of Data Mining …, 2021 - inderscienceonline.com
Male Germline Stem (GS) cells are responsible for sperm production in males throughout
the adulthood. Under in vitro culture conditions, these cells can undergo the reprogramming …