The human lung plays vital roles in respiration, host defense, and basic physiology. Recent
technological advancements such as single-cell RNA sequencing and genetic lineage …

Bronchopulmonary dysplasia (BPD) is the most common complication of preterm birth. Up to
1/3 of children with BPD develop pulmonary hypertension (PH). PH increases mortality, the …

Pulmonary fibrosis results from dysregulated lung repair and involves multiple cell types.
The role of endothelial cells (EC) in lung fibrosis is poorly understood. Using single cell RNA …

Abstract Endothelial Progenitor Cells (EPCs) are precursor cells of endothelial cells (ECs),
which can differentiate into vascular ECs, protect from endothelial dysfunction and tissue …

Accurate cell type identification is a key and rate-limiting step in single-cell data analysis.
Single-cell references with comprehensive cell types, reproducible and functionally …

Pulmonary endothelial progenitor cells (EPCs) are critical for neonatal lung angiogenesis
and represent a subset of general capillary cells (gCAPs). Molecular mechanisms through …

Rationale: Alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV) is a
lethal developmental disorder of lung morphogenesis caused by insufficiency of FOXF1 …

Background: Pulmonary hypertension (PH) is a common complication in patients with
alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV), a severe …

Pulmonary hypertension (PH) is a progressive disease characterised by elevated pulmonary
arterial pressure and right-sided heart failure. While conventional drug therapies, including …

Rationale: Alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV) is
linked to heterozygous mutations in the FOXF1 (Forkhead Box F1) gene, a key …