Molecular imaging of bone metastases and their response to therapy

GJR Cook, V Goh - Journal of Nuclear Medicine, 2020 - Soc Nuclear Med
Bone metastases are common, especially in more prevalent malignancies such as breast
and prostate cancer. They cause significant morbidity and draw on health-care resources …

Application of PET tracers in molecular imaging for breast cancer

J Boers, EFJ de Vries, AWJM Glaudemans… - Current oncology …, 2020 - Springer
Abstract Purpose of Review Molecular imaging with positron emission tomography (PET) is
a powerful tool to visualize breast cancer characteristics. Nonetheless, implementation of …

Input function and modeling for determining bone metabolic flux using [18F] sodium fluoride PET imaging: A step‐by‐step guide

T Puri, ML Frost, AEB Moore, GJR Cook… - Medical …, 2023 - Wiley Online Library
Studies of skeletal metabolism using measurements of bone metabolic flux (Ki) obtained
with [18F] sodium fluoride ([18F] NaF) positron emission tomography (PET) scans have been …

Utility of a simplified [18F] sodium fluoride PET imaging method to quantify bone metabolic flux for a wide range of clinical applications

T Puri, ML Frost, AEB Moore, A Choudhury… - Frontiers in …, 2023 - frontiersin.org
We review the rationale, methodology, and clinical utility of quantitative [18F] sodium fluoride
([18F] NaF) positron emission tomography-computed tomography (PET-CT) imaging to …

Emerging role of 18F-NaF PET/computed tomographic imaging in osteoporosis: a potential upgrade to the osteoporosis toolbox

AJ Sheppard, SS Paravastu, NM Wojnowski… - PET …, 2023 - pmc.ncbi.nlm.nih.gov
Osteoporosis is the most common metabolic bone disorder, with an estimated prevalence of
13.1% to 27.1% of women and 3.3% to 5.7% of men over the age of 50 affected. 1, 2 As a …

[18F] Sodium Fluoride PET Kinetic Parameters in Bone Imaging

T Puri, ML Frost, GJ Cook, GM Blake - Tomography, 2021 - mdpi.com
This report describes the significance of the kinetic parameters (k-values) obtained from the
analysis of dynamic positron emission tomography (PET) scans using the Hawkins model …

Innovations in positron emission tomography and state of the art in the evaluation of breast cancer treatment response

L Castorina, AD Comis, A Prestifilippo… - Journal of Clinical …, 2023 - mdpi.com
The advent of hybrid Positron Emission Tomography/Computed Tomography (PET/CT) and
PET/Magnetic Resonance Imaging (MRI) scanners resulted in an increased clinical …

68Ga-bisphosphonates for the imaging of extraosseous calcification by positron emission tomography

GP Keeling, F Baark, OL Katsamenis, J Xue… - Scientific Reports, 2023 - nature.com
Abstract Radiolabelled bisphosphonates (BPs) and [18F] NaF (18F-fluoride) are the two
types of radiotracers available to image calcium mineral (eg bone), yet only [18F] NaF has …

Imaging of bone metastases in breast cancer

GJR Cook - Seminars in Nuclear Medicine, 2022 - Elsevier
Bone metastases are a common site of spread in advanced breast cancer and responsible
for morbidity and high health care costs. Imaging contributes to staging and response …

A comprehensive review of the role of bone marrow biopsy and PET-CT in the evaluation of bone marrow involvement in adults newly diagnosed with DLBCL

R Alyamany, R El Fakih, A Alnughmush… - Frontiers in …, 2024 - frontiersin.org
Diffuse large B cell lymphoma (DLBCL) is one of the most prevalent subtypes of non-
Hodgkin lymphoma (NHL) and is known for commonly infiltrating extra-nodal sites. The …