Covering: 1958 to June 2018 Phenyl-γ-valerolactones (PVLs) and their related
phenylvaleric acids (PVAs) are the main metabolites of flavan-3-ols, the major class of …

As people age they become increasingly susceptible to chronic and extremely debilitating
brain diseases. The precise cause of the neuronal degeneration underlying these disorders …

Recent advances in metabolomics allow for more objective assessment of contemporary
food exposures, which have been proposed as an alternative or complement to self …

Gallic acid (GA), a naturally abundant plant phenolic compound in vegetables and fruits, has
been shown to have potent anti-oxidative and anti-obesity activity. However, the effects of …

Background: Nontargeted metabolite profiling allows for concomitant examination of a wide
range of metabolite species, elucidating the metabolic alterations caused by dietary …

Gut microbiota has recently been proposed as a crucial environmental factor in the
development of metabolic diseases such as obesity and type 2 diabetes, mainly due to its …

Metabolomics, the comprehensive analysis of metabolites in a biological system, provides
detailed information about the biochemical/physiological status of a biological system, and …

Blood sample preparation before LC-MS metabolomic fingerprinting is one of the most
challenging and error-prone parts of the analytical procedure. Besides proteins …

Recent evidence suggests that gut microbiota-derived metabolites affect many biological
processes of the host, including appetite control and weight management. Dysbiosis of the …

Abstract Proton Nuclear Magnetic Resonance (NMR) spectroscopic analysis of urine
generates rich but complex spectra. Retrieving metabolite information from such spectra is …