Melanogenesis is a process to synthesize melanin, which is a primary responsible for the
pigmentation of human skin, eye and hair. Although numerous enzymatic catalyzed and …

Benzene causes acute myeloid leukemia and probably other hematological malignancies.
As benzene also causes hematotoxicity even in workers exposed to levels below the US …

Background Melanin plays an important role in protecting human skin, while excessive
synthesis of melanin can cause abnormal pigmentation and induce skin diseases. Long …

Benzene exposure is associated with acute myeloid leukemia (AML), myelodysplastic
syndromes (MDS), and probably lymphoma and childhood leukemia. Biological plausibility …

The development of Tyrosinase inhibitors (TYRIs) could represent an efficacious strategy for
pharmacological intervention on skin pathologies related to aberrant production of melanin …

The biological effect of benzene on the hematopoietic system has been known for over a
century. The rapid advancement in understanding the biology of hematopoietic stem cells …

Benzene, a ubiquitous environmental chemical, is known to cause immune dysfunction and
developmental defects. This study aims to investigate the relation between benzene …

Simple Summary Benzene is produced by diverse petroleum transformation processes and
it is widely employed in industry despite its oncogenic effects. In fact, occupational exposure …

Benzene is a ubiquitous, occupational, and environmental hematotoxic and leukemogen.
Damage to hematopoietic stem cells (HSCs) induced by benzene and its metabolites is a …

Hematopoietic stem cells/progenitor cells (HSC/HPCs) orchestrate the hematopoietic
process, effectively regulated by the hematopoietic niche under normal and stressed …