Applications of cucurbiturils in medicinal chemistry and chemical biology

D Das, KI Assaf, WM Nau - Frontiers in chemistry, 2019 - frontiersin.org
The supramolecular chemistry of cucurbit [n] urils (CB n) has been rapidly developing to
encompass diverse medicinal applications, including drug formulation and delivery …

[HTML][HTML] Combating antibiotic resistance: Current strategies for the discovery of novel antibacterial materials based on macrocycle supramolecular chemistry

L Gao, H Wang, B Zheng, F Huang - Giant, 2021 - Elsevier
In the fight of bacteria with human, bacteria have regained the upper hand by development
of antibiotic resistance. The emergence of resistance has outpaced the development of new …

Cucurbituril-based supramolecular assemblies: Prospective on drug delivery, sensing, separation, and catalytic applications

N Barooah, J Mohanty, AC Bhasikuttan - Langmuir, 2022 - ACS Publications
Precise control over the stimuli-responsive noncovalent interactions operative in a complex
molecular system has emerged as a convenient way to realize applications in the detection …

Controllable hydrogen bonded self-association for the formation of multifunctional antimicrobial materials

LJ White, JE Boles, N Allen, LS Alesbrook… - Journal of Materials …, 2020 - pubs.rsc.org
SSAs are a class of supramolecular self-associating amphiphilic salt, the anionic component
of which contains a covalently bound hydrogen bond donor–acceptor motif. This results in a …

Towards the Prediction of Antimicrobial Efficacy for Hydrogen Bonded, Self‐Associating Amphiphiles

N Allen, LJ White, JE Boles, GT Williams… - …, 2020 - Wiley Online Library
Herein we report 50 structurally related supramolecular self‐associating amphiphilic (SSA)
salts and related compounds. These SSAs are shown to act as antimicrobial agents, active …

Metal-free supramolecular catalytic hydrolysis of ammonia borane through cucurbituril nanocavitands

P Ruz, S Banerjee, R Khurana, N Barooah… - … Applied Materials & …, 2021 - ACS Publications
Ammonia borane (AB) is considered a potential “on-board” hydrogen storage material.
However, its implementation as a hydrogen reservoir in fuel cells is lacking due to the …

Supramolecular assembly of coumarin 7 with sulfobutylether-β-cyclodextrin for biomolecular applications

TC Gayathry, M Gaur, L Mishra, M Mishra… - Frontiers in …, 2023 - frontiersin.org
Coumarins, in general, exhibit a wide range of photophysical characteristics and are highly
sensitive to their microenvironment, and, therefore, their fluorescence characteristics have …

Unveiling host–guest–solvent interactions in solution by identifying highly unstable host–guest configurations in thermal non-equilibrium gas phase

H Choi, YH Oh, S Park, SS Lee, HB Oh, S Lee - Scientific Reports, 2022 - nature.com
We propose a novel scheme of examining the host–guest–solvent interactions in solution
from their gas phase structures. By adopting the permethylated β-cyclodextrin (perm β-CD) …

Comparative electrochemical study of veterinary drug danofloxacin at glassy carbon electrode and electrified liquid–liquid interface

K Rudnicki, S Budzyńska, S Skrzypek, L Poltorak - Scientific Reports, 2024 - nature.com
This work compares the electroanalytical performance of two electroanalytical systems
based on (1) the glassy carbon electrode (GCE), and (2) the electrified liquid–liquid interface …

Supramolecule-driven host–guest Co-crystallization of cyclic polyphenols with anti-fibrotic pharmaceutical drug

SD Panigrahi, CM Mayhan, AA Dar… - Crystal Growth & …, 2023 - ACS Publications
Host–guest complexes are of interest as supramolecular drugs in pharmaceutical sciences
because the activity of antibacterial agents can be enhanced upon complexation with …