Pseudomonas aeruginosa is an opportunistic pathogen causing nosocomial infections in
severely ill and immunocompromised patients. Ubiquitously disseminated in the …

Pyocyanin has recently emerged as an important virulence factor produced by
Pseudomonas aeruginosa. The redox-active tricyclic zwitterion has been shown to have a …

Pseudomonas aeruginosa is a metabolically versatile bacterium that can cause a wide
range of severe opportunistic infections in patients with serious underlying medical …

Neutrophils (also called polymorphonuclear leukocytes, PMNs) are the most abundant white
blood cells in humans and play a central role in innate host defense. Another distinguishing …

The predominant definition of apoptosis considers that the elimination of the apoptosing cell
is by heterolytic degradation following phagocytosis by an assisting scavenger …

Recent advances in defining the molecular signaling pathways that regulate the
phagocytosis of apoptotic cells have improved our understanding of this complex and …

Studies of biopsies from infectious sites, explanted tissue and medical devises have
provided evidence that biofilms are the underlying cause of a variety of tissue-associated …

Pseudomonas aeruginosa is a complex gram-negative facultative anaerobe replete with a
variety of arsenals to activate, modify, and destroy host defense mechanisms. The microbe is …

The mechanisms of chronic infections caused by opportunistic pathogens are of keen
interest to both researchers and health professionals globally. Typically, chronic infectious …

Acute and chronic inflammatory responses in the lung are associated with the accumulation
of large quantities of immune and structural cells undergoing apoptosis, which need to be …