[HTML][HTML] Co-prescription of dual-antiplatelet therapy and proton pump inhibitors: current guidelines

H Saven, L Zhong, IM McFarlane - Cureus, 2022 - ncbi.nlm.nih.gov
Dual-antiplatelet therapy (DAPT) prevents thrombotic complications associated with
coronary artery disease, acute coronary syndrome, and stent thrombosis following the …

Who gets prescriptions for proton pump inhibitors and why? A drug-utilization study with claims data in Bavaria, Germany, 2010–2018

IM Rückert-Eheberg, M Nolde, N Ahn… - European journal of …, 2022 - Springer
Abstract Purpose The German annual drug prescription-report has indicated overuse of
proton pump inhibitors (PPIs) for many years; however, little was known about the …

Proton pump inhibitors and in-hospital gastrointestinal bleeding in patients with acute coronary syndrome receiving dual antiplatelet therapy

M Zhou, J Zhang, J Liu, SC Smith Jr, C Ma, J Ge… - Mayo Clinic …, 2022 - Elsevier
Objective To evaluate the association between proton pump inhibitor (PPI) use and in-
hospital gastrointestinal (GI) bleeding in patients with acute coronary syndrome (ACS) taking …

Impact of concomitant use of proton pump inhibitors and clopidogrel on recurrent stroke and myocardial infarction

YK Lee, HS Lim, YI Choi, EJ Choe, S Kim, SC You… - Pharmaceuticals, 2023 - mdpi.com
Background/Aims: Conflicting results have been reported regarding the interaction between
proton pump inhibitors (PPIs) and clopidogrel. We investigated whether concomitant PPI use …

Use of clopidogrel and proton pump inhibitors alone or in combinations in persons with diabetes in Denmark; potential for CYP2C19 genotype-guided drug therapy

N Westergaard, L Tarnow, C Vermehren - Metabolites, 2021 - mdpi.com
Background: Clopidogrel and proton pump inhibitors (PPIs) are among the most used drugs
in Denmark for which there exists pharmacogenomics (PGx)-based dosing guidelines and …

Concomitant use of drugs known to cause interactions with oral antiplatelets—polypharmacy in acute coronary syndrome outpatients in Finland

T Prami, H Khanfir, P Hasvold, E Reissell… - European Journal of …, 2020 - Springer
Purpose Use of oral antiplatelets (OAPs) is essential for preventing thrombotic events in
patients with acute coronary syndrome (ACS). Effects of clopidogrel, prasugrel, and …

The clinical impact of proton pump inhibitors when co-administered with dual antiplatelet therapy in patients having acute myocardial infarction with low risk of …

W Shi, L Ni, J Yang, X Fan, M Yu, H Yang… - Frontiers in …, 2021 - frontiersin.org
Background: The latest guidelines recommend the use of proton pump inhibitors (PPIs) to
minimize gastrointestinal bleeding (GIB) in patients receiving dual antiplatelet therapy …

[PDF][PDF] 表没食子儿茶素没食子酸酯通过抑制心肌细胞凋亡缓解心肌缺血再灌注损伤的机制研究

符武岛, 曾敏, 陈娟, 冯光球, 管频, 钟春荣 - 中国药房, 2019 - china-pharmacy.com
摘要目的: 探讨表没食子儿茶素没食子酸酯(EGCG) 对心肌缺血再灌注损伤的保护作用及其可能
机制. 方法: 以叔丁基过氧化氢(TBHP) 处理H9C2 心肌细胞构建缺血再灌注细胞模型, 采用MTS …

Trends in prescribing volumes and costs of proton pump inhibitors in three outpatient specialties: a three-year retrospective study in a tertiary hospital in Thailand

F Yusof, S Sanguanhong, S Soorapan… - … Journal of Pharmacy …, 2023 - academic.oup.com
Objectives The study determined a comparative three-year trend in prescribing volumes and
costs of proton pump inhibitors in three outpatient specialties of a tertiary hospital. Methods …

Metabolomics analysis of the effect of hydrogen-rich water on myocardial ischemia-reperfusion injury in rats

L Li, T Liu, L Liu, Z Zhang, S Li, Z Zhang… - Journal of Bioenergetics …, 2020 - Springer
To investigate the effect of hydrogen-rich water on myocardial tissue metabolism in a
myocardial ischemia-reperfusion injury (MIRI) rat model. Twelve rats were randomly divided …