Simple Summary All cells are covered in a thick layer of sugar molecules known as glycans.
Changes to this sugar coat are common in cancer, and in particular cancer cells often …

Aberrant glycosylation is a key feature of malignant transformation. Hypersialylation, the
enhanced expression of sialic acid-terminated glycoconjugates on the cell surface, has …

Intestinal mucus forms the first line of defense against bacterial invasion while providing
nutrition to support microbial symbiosis. How the host controls mucus barrier integrity and …

In recent years, the strategy for tumor therapy has changed from focusing on the direct killing
effect of different types of therapeutic agents on cancer cells to the new mainstream of multi …

Many tumour antigens that do not arise from cancer cell-specific mutations are targets of
humoral and cellular immunity despite their expression on non-malignant cells. Thus, in …

Background Ulcerative colitis (UC) accounts for the untreatable illness nowadays. Bloody
stools are the primary symptom of UC, and the first-line drugs used to treat UC are …

Background: Ulcerative colitis (UC) is a chronic recurrent inflammatory bowel disease (IBD).
The conventional drugs for UC may induce severe side effects. Herbal medicine is …

Patients with inflammatory bowel disease (IBD) have increased incidence of colorectal
cancer (CRC). IBD-associated cancer follows a well-characterized sequence of intestinal …

The preventive effect and molecular mechanism of lycopene (LP) in dextran sulfate sodium
(DSS)-induced ulcerative colitis (UC) in mice were evaluated. Compared to the DSS group …

Advances in bioanalytical technology have accelerated the analysis of complex protein
glycosylation, which is beneficial to understand glycosylation in drug discovery and disease …