Chemotherapy‐induced peripheral neuropathy: a current review

NP Staff, A Grisold, W Grisold… - Annals of …, 2017 - Wiley Online Library
Chemotherapy‐induced peripheral neuropathy (CIPN) is a common dose‐limiting side effect
experienced by patients receiving treatment for cancer. Approximately 30 to 40% of patients …

Next-generation sequencing in oncology: genetic diagnosis, risk prediction and cancer classification

R Kamps, RD Brandão, BJ van den Bosch… - International journal of …, 2017 - mdpi.com
Next-generation sequencing (NGS) technology has expanded in the last decades with
significant improvements in the reliability, sequencing chemistry, pipeline analyses, data …

Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2D6, CYP3A4 and CYP1A2 and antipsychotics

L Beunk, M Nijenhuis, B Soree… - European Journal of …, 2024 - nature.com
Abstract The Dutch Pharmacogenetics Working Group (DPWG) aims to facilitate
pharmacogenetics implementation in clinical practice by developing evidence-based …

Long-term chemotherapy-induced peripheral neuropathy among breast cancer survivors: prevalence, risk factors, and fall risk

T Bao, C Basal, C Seluzicki, SQ Li, AD Seidman… - Breast cancer research …, 2016 - Springer
Chemotherapy-induced peripheral neuropathy (CIPN) is a common toxicity associated with
chemotherapy, but researchers rarely study its risk factors, fall risk, and prevalence in long …

Pathogenesis of paclitaxel-induced peripheral neuropathy: A current review of in vitro and in vivo findings using rodent and human model systems

NP Staff, JC Fehrenbacher, M Caillaud, MI Damaj… - Experimental …, 2020 - Elsevier
Abstract Paclitaxel (Brand name Taxol) is widely used in the treatment of common cancers
like breast, ovarian and lung cancer. Although highly effective in blocking tumor progression …

Clinical pharmacokinetics of paclitaxel monotherapy: an updated literature review

TB Stage, TK Bergmann, DL Kroetz - Clinical pharmacokinetics, 2018 - Springer
Paclitaxel is an anticancer agent efficacious in the treatment of ovarian, breast, and lung
cancer. Due to a strong link between the pharmacokinetics and therapeutic efficacy of …

Chemotherapy‐induced neuropathies—a growing problem for patients and health care providers

M Banach, JK Juranek, AL Zygulska - Brain and behavior, 2017 - Wiley Online Library
Introduction Chemotherapy‐induced neuropathies are one of the most common side effects
of cancer treatment, surpassing bone marrow suppression and kidney dysfunction …

Genome-wide association studies for taxane-induced peripheral neuropathy in ECOG-5103 and ECOG-1199

BP Schneider, L Li, M Radovich, F Shen, KD Miller… - Clinical Cancer …, 2015 - AACR
Purpose: Taxane-induced peripheral neuropathy (TIPN) is an important survivorship issue
for many cancer patients. Currently, there are no clinically implemented biomarkers to …

[HTML][HTML] Novel genetic and epigenetic factors of importance for inter-individual differences in drug disposition, response and toxicity

VM Lauschke, Y Zhou, M Ingelman-Sundberg - Pharmacology & …, 2019 - Elsevier
Individuals differ substantially in their response to pharmacological treatment. Personalized
medicine aspires to embrace these inter-individual differences and customize therapy by …

Taxane-induced peripheral neurotoxicity

R Velasco, J Bruna - Toxics, 2015 - mdpi.com
Taxane-derived agents are chemotherapy drugs widely employed in cancer treatment.
Among them, paclitaxel and docetaxel are most commonly administered, but newer …