Systemic vasculitis are rare heterogeneous disorders potentially involving any organ and
system with a relevant burden of mortality and comorbidity. As in the previous annual …

Objective To summarise and update evidence to inform the 2022 update of the EULAR
recommendations for the management of antineutrophil cytoplasm antibody-associated …

Updated guidelines on the management of antineutrophil cytoplasmic antibody (ANCA)-
associated vasculitis (AAV) were released in 2021 by the American College of …

ANCA-associated vasculitides (AAV) are a group of rare, primary, systemic necrotizing small-
vessel vasculitides. Granulomatosis with polyangiitis and microscopic polyangiitis account …

Background Ocular manifestations of granulomatosis with polyangiitis (GPA) have been
reported in a limited number of studies and with largely variable frequency. Here we report …

Background Severe renal impairment is a common complication of anti-neutrophil
cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and is associated with poor …

Before becoming a cornerstone in the treatment of numerous immune-mediated diseases,
mycophenolate mofetil (MMF) was first introduced as an immunosuppressive agent in …

Background The ACR in 2021 and the EULAR in 2022 published recommendations for
management of ANCA-associated vasculitis. Given the differences in the demographic …

Abstract Purpose of Review Pauci-immune crescentic glomerulonephritis is the hallmark
finding in ANCA-associated vasculitis (AAV) when the kidneys are affected. The rationale for …

We have made significant headway in our ability to induce and maintain remission in
patients with GPA and MPA. With increased understanding of the pathogenesis of AAV …