[HTML][HTML] Safe-and-sustainable-by-design: State of the art approaches and lessons learned from value chain perspectives

C Apel, K Kümmerer, A Sudheshwar, B Nowack… - Current Opinion in …, 2024 - Elsevier
Abstract Safe-and-sustainable-by-design (SSbD) is central in the European Chemicals
Strategy for Sustainability, yet a common understanding of what SSbD is in concept and in …

Analyzing the surface of functional nanomaterials—how to quantify the total and derivatizable number of functional groups and ligands

D Geißler, N Nirmalananthan-Budau, L Scholtz… - Microchimica Acta, 2021 - Springer
Functional nanomaterials (NM) of different size, shape, chemical composition, and surface
chemistry are of increasing relevance for many key technologies of the twenty-first century …

[HTML][HTML] Safe-and sustainable-by-design: The case of Smart Nanomaterials. A perspective based on a European workshop

A Mech, S Gottardo, V Amenta, A Amodio, S Belz… - Regulatory Toxicology …, 2022 - Elsevier
Abstract The European Commission's Green Deal is a major policy initiative aiming to
achieve a climate-neutral, zero-pollution, sustainable, circular and inclusive economy …

Learning from Safe-by-Design for Safe-and-Sustainable-by-Design: Mapping the current landscape of Safe-by-Design reviews, case studies, and frameworks

A Sudheshwar, C Apel, K Kümmerer, Z Wang… - Environment …, 2024 - Elsevier
With the introduction of the European Commission's “Safe and Sustainable-by-
Design”(SSbD) framework, the interest in understanding the implications of safety and …

[HTML][HTML] Safe-by-Design part II: A strategy for balancing safety and functionality in the different stages of the innovation process

I Tavernaro, S Dekkers, LG Soeteman-Hernández… - NanoImpact, 2021 - Elsevier
Manufactured nanomaterials have the potential to impact an exceedingly wide number of
industries and markets ranging from energy storage, electronic and optical devices, light …

Nanosafety: an evolving concept to bring the safest possible nanomaterials to society and environment

F Lebre, N Chatterjee, S Costa… - Nanomaterials, 2022 - mdpi.com
The use of nanomaterials has been increasing in recent times, and they are widely used in
industries such as cosmetics, drugs, food, water treatment, and agriculture. The rapid …

The meaning of life… cycles: lessons from and for safe by design studies

JB Guinée, R Heijungs, MG Vijver… - Green …, 2022 - pubs.rsc.org
The concepts of Safe by Design (SbD) and Safe and Sustainable by Design (SSbD) are
receiving increasing attention. The definitions of both concepts include the term 'life cycle'in …

Status, implications and challenges of European safe and sustainable by design paradigms applicable to nanomaterials and advanced materials

I Furxhi, A Costa, S Vázquez-Campos… - RSC …, 2023 - pubs.rsc.org
Current European (EU) policies, such as the Green Deal, envisage safe and sustainable by
design (SSbD) practices for the management of chemicals, which cogently entail …

[HTML][HTML] Integrative approach in a safe by design context combining risk, life cycle and socio-economic assessment for safer and sustainable nanomaterials

B Salieri, L Barruetabeña, I Rodríguez-Llopis… - NanoImpact, 2021 - Elsevier
Moving towards safe and sustainable innovations is an international policy ambition. In the
on-hand manuscript, a concept combining safe by design and sustainability was …

[HTML][HTML] Pro-inflammatory and genotoxic responses by metal oxide nanomaterials in alveolar epithelial cells and macrophages in submerged condition and air-liquid …

E Di Ianni, JS Erdem, S Narui, H Wallin, I Lynch… - Toxicology in Vitro, 2024 - Elsevier
Studies on in vitro-in vivo correlations of inflammatory and genotoxic responses are needed
to advance new approach methodologies. Here, we assessed pro-inflammatory and …