Short Tandem Repeats in the era of next-generation sequencing: from historical loci to population databases

K Uguen, JL Michaud, E Génin - European Journal of Human Genetics, 2024 - nature.com
In this study, we explore the landscape of short tandem repeats (STRs) within the human
genome through the lens of evolving technologies to detect genomic variations. STRs, which …

An ELOVL2-based epigenetic clock for forensic age prediction: a systematic review

E Paparazzo, V Lagani, S Geracitano… - International Journal of …, 2023 - mdpi.com
The prediction of chronological age from methylation-based biomarkers represents one of
the most promising applications in the field of forensic sciences. Age-prediction models …

Forensic DNA Phenotyping: Genes and Genetic Variants for Eye Color Prediction

D Brancato, E Coniglio, F Bruno, V Agostini, S Saccone… - Genes, 2023 - mdpi.com
In recent decades, the use of genetic polymorphisms related to specific phenotypes, such as
eye color, has greatly contributed to the development of the research field called forensic …

Artificial intelligence and forensic genetics: current applications and future perspectives

F Sessa, M Esposito, G Cocimano, S Sablone… - Applied Sciences, 2024 - mdpi.com
The term artificial intelligence (AI) was coined in the 1950s and it has successfully made its
way into different fields of medicine. Forensic sciences and AI are increasingly intersecting …

Open-Access Worldwide Population STR Database Constructed Using High-Coverage Massively Parallel Sequencing Data Obtained from the 1000 Genomes Project

TS Frontanilla, G Valle-Silva, J Ayala… - Genes, 2022 - mdpi.com
Achieving accurate STR genotyping by using next-generation sequencing data has been
challenging. To provide the forensic genetics community with a reliable open-access STR …

[HTML][HTML] Applications and Performance of Precision ID GlobalFiler NGS STR, Identity, and Ancestry Panels in Forensic Genetics

S Pedroza Matute, S Iyavoo - Genes, 2024 - mdpi.com
Short Tandem Repeat (STR) testing via capillary electrophoresis is undoubtedly the most
popular forensic genetic testing method. However, its low multiplexing capabilities and …

Solving the twin paradox-forensic strategies to identify the identical twins

M Aourangzaib, M Chandra, R Maham, A Naz… - Forensic Science …, 2024 - Elsevier
Identical twins are also called monozygotic twins which originate from the same zygote that
possesses the same genetic make-up. To discriminate between identical monozygotic twins …

Advances in forensic genetics: Exploring the potential of long read sequencing

MR Ferreira, TMT Carratto, TSF Recalde… - Forensic Science …, 2024 - Elsevier
DNA-based technologies have been used in forensic practice since the mid-1980s. While
PCR-based STR genotyping using Capillary Electrophoresis remains the gold standard for …

[HTML][HTML] Benchmarking for genotyping and imputation using degraded DNA for forensic applications across diverse populations

EI Zavala, RV Rohlfs, P Moorjani - Forensic Science International: Genetics, 2025 - Elsevier
Advancements in sequencing and laboratory technologies have enabled forensic genetic
analysis on increasingly low quality and degraded DNA samples. However, existing …

The Development and Characterisation of ssDNA Aptamers via a Modified Cell-SELEX Methodology for the Detection of Human Red Blood Cells

H Costanzo, J Gooch, S Tungsirisurp… - International Journal of …, 2024 - mdpi.com
Blood is one of the most commonly found biological fluids at crime scenes, with the detection
and identification of blood holding a high degree of evidential value. It can provide not only …