Covering: up to April 2014 The development of drugs with broad-spectrum antiviral activities
is a long pursued goal in drug discovery. It has been shown that blocking co-opted host …

Many natural lectins have been reported to have antiviral activity. As some of these have
been put forward as potential development candidates for preventing or treating viral …

Virus entry into a susceptible host cell is the first step in the formation of all viral diseases.
Controlling viral infections by disrupting viral entry is advantageous for antibody-mediated …

Macroalgae are increasingly viewed as a source of secondary metabolites with great
potential for the development of new drugs. In this development, in vitro studies are only the …

Griffithsin (GRFT), an algae-derived lectin, is one of the most potent viral entry inhibitors
discovered to date. It is currently being developed as a microbicide with broad-spectrum …

Highly pathogenic human coronaviruses associated with a severe respiratory syndrome,
including Middle East respiratory syndrome coronavirus (MERS-CoV), have recently …

Herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) are highly prevalent within the
human population and are characterized by lifelong infections and sporadic recurrences …

COVID-19—a severe acute respiratory syndrome disease caused by coronavirus 2 (SARS-
CoV-2)—has recently attracted global attention, due to its devastating impact, to the point of …

Zika virus (ZIKV) remained largely quiescent for nearly six decades after its first appearance
in 1947. ZIKV reappeared after 2007, resulting in a declaration of an international “public …

The present outburst of coronavirus-associated (SARS-CoV-2) acute respiratory disease
coronavirus disease 19 (COVID-19) in December 2019 in Wuhan, China is the third …