The role of mTOR and eIF signaling in benign endometrial diseases

TS Driva, C Schatz, M Sobočan… - International Journal of …, 2022 - mdpi.com
Adenomyosis, endometriosis, endometritis, and typical endometrial hyperplasia are
common non-cancerous diseases of the endometrium that afflict many women with life …

The Spectrum of Fusions Occurring in Non–Smooth Muscle Mesenchymal Uterine Tumors: A Review of the Current Knowledge

P Dundr, R Matěj, J Hojný, N Hájková… - … of Pathology & …, 2025 - meridian.allenpress.com
Context.—Non–smooth muscle uterine sarcomas are mostly represented by low-grade
endometrial stromal sarcoma. However, several other rare, distinct types of uterine sarcoma …

A clinicopathologic and molecular characterization of uterine sarcomas classified as malignant PEComa

WJ Anderson, F Dong, CDM Fletcher… - The American Journal …, 2023 - journals.lww.com
Perivascular epithelioid cell tumors (PEComas) are a distinctive group of mesenchymal
neoplasms that demonstrate features of smooth muscle and melanocytic differentiation …

Uterine mesenchymal tumours harboring the KAT6B/A:: KANSL1 gene fusion represent a distinct type of uterine sarcoma based on DNA methylation profiles

FKF Kommoss, A Charbel, DL Kolin, BE Howitt… - Virchows Archiv, 2024 - Springer
Uterine mesenchymal tumours harboring KAT6B/A:: KANSL1 gene fusions typically exhibit
histological and immunophenotypic overlap with endometrial stromal and smooth muscle …

Novel therapeutics in the treatment of uterine sarcoma

S Bose, GK Schwartz, M Ingham - American Society of Clinical …, 2022 - ascopubs.org
Uterine sarcomas reflect the diversity of sarcoma as a whole. The most common histologies
include leiomyosarcoma, high-and low-grade endometrial stromal sarcoma, and …

Expanding the molecular spectrum of gene fusions in endometrial stromal sarcoma: novel subunits of the chromatin remodeling complexes PRC2 and NuA4/TIP60 as …

JK Dermawan, N Dashti, S Chiang… - Genes …, 2023 - Wiley Online Library
Endometrial stromal sarcomas (ESS) are morphologically and molecularly heterogeneous.
We report novel gene fusions (EPC1:: EED, EPC1:: EZH2, ING3:: PHF1) identified by …

Targeted RNA sequencing highlights a diverse genomic and morphologic landscape in low-grade endometrial stromal sarcoma, including novel fusion genes

DL Kolin, MR Nucci, G Turashvili, SJ Song… - The American Journal …, 2024 - journals.lww.com
Low-grade endometrial stromal sarcoma (LGESS) represents a morphologically and
genetically heterogenous mesenchymal neoplasm. Previous work has shown that …

[HTML][HTML] Isolation of proteins on chromatin (iPOC) reveals signaling pathway-dependent alterations in the DNA-bound proteome

H Wang, AA Syed, J Krijgsveld… - Molecular & Cellular …, 2025 - Elsevier
Signaling pathways often convergence on transcription factors (TFs) and other DNA-binding
proteins (DBPs) that regulate chromatin structure and gene expression, thereby governing a …

Feasibility of Longitudinal ctDNA Assessment in Patients with Uterine and Extra-Uterine Leiomyosarcoma

M Zhou, N Bui, R Rathore, S Sudhaman, GV George… - Cancers, 2022 - mdpi.com
Simple Summary Leiomyosarcomas are the most common soft tissue sarcomas (STS)
subtype characterized by increased aggressiveness and early relapse. Current surveillance …

Sarcomas With RAD51B Fusions Are Associated With a Heterogeneous Phenotype

HY Chang, J Dermawan, A Sharma, B Dickson… - Modern Pathology, 2024 - Elsevier
RAD51B-rearranged sarcomas are rare neoplasms that exhibit a heterogeneous
morphology. To date, 6 cases have been reported, all involving the uterus, including 4 …