Safety, tolerability, and risks associated with first-and second-generation antipsychotics: a state-of-the-art clinical review

M Solmi, A Murru, I Pacchiarotti… - … and clinical risk …, 2017 - Taylor & Francis
Since the discovery of chlorpromazine (CPZ) in 1952, first-generation antipsychotics (FGAs)
have revolutionized psychiatric care in terms of facilitating discharge from hospital and …

Medication-induced tardive dyskinesia: a review and update

EM Cornett, M Novitch, AD Kaye, V Kata… - Ochsner …, 2017 - ochsnerjournal.org
Background: Tardive dyskinesia (TD) is a movement disorder that causes involuntary,
repetitive body movements and is commonly seen in patients who are on long-term …

Phosphoinositides: regulators of nervous system function in health and disease

P Raghu, A Joseph, H Krishnan, P Singh… - Frontiers in molecular …, 2019 - frontiersin.org
Phosphoinositides, the seven phosphorylated derivatives of phosphatidylinositol have
emerged as regulators of key sub-cellular processes such as membrane transport …

[HTML][HTML] Second hit hypothesis in dystonia: Dysfunctional cross talk between neuroplasticity and environment?

L Rauschenberger, S Knorr, A Pisani, M Hallett… - Neurobiology of …, 2021 - Elsevier
One of the great mysteries in dystonia pathophysiology is the role of environmental factors in
disease onset and development. Progress has been made in defining the genetic …

Pharmacogenetics of tardive dyskinesia: an updated review of the literature

RK Lanning, CC Zai, DJ Müller - Pharmacogenomics, 2016 - Taylor & Francis
Tardive dyskinesia (TD) is a serious and potentially irreversible side effect of long-term
exposure to antipsychotic medication characterized by involuntary trunk, limb and orofacial …

NRG1, PIP4K2A, and HTR2C as Potential Candidate Biomarker Genes for Several Clinical Subphenotypes of Depression and Bipolar Disorder

A Levchenko, NM Vyalova, T Nurgaliev… - Frontiers in …, 2020 - frontiersin.org
GSK3B, BDNF, NGF, NRG1, HTR2C, and PIP4K2A play important roles in molecular
mechanisms of psychiatric disorders. GSK3B occupies a central position in these molecular …

Tardive dyskinesia in older persons taking antipsychotics

L Citrome, SH Isaacson, D Larson… - … Disease and Treatment, 2021 - Taylor & Francis
Tardive dyskinesia (TD) is a hyperkinetic movement disorder caused by the use of
dopamine receptor-blocking agents (DRBAs), a category of medications that includes first …

Opening up new horizons for psychiatric genetics in the Russian Federation: moving toward a national consortium

OY Fedorenko, VE Golimbet, SА Ivanova… - Molecular …, 2019 - nature.com
We provide an overview of the recent achievements in psychiatric genetics research in the
Russian Federation and present genotype-phenotype, population, epigenetic, cytogenetic …

Genome wide study of tardive dyskinesia in schizophrenia

K Lim, M Lam, C Zai, J Tay, N Karlsson… - Translational …, 2021 - nature.com
Tardive dyskinesia (TD) is a severe condition characterized by repetitive involuntary
movement of orofacial regions and extremities. Patients treated with antipsychotics typically …

Клинические, эпидемиологические и биологические предпосылки адаптации больных шизофренией как основа персонифицированного подхода к …

АВ Семке, ОЮ Федоренко, ОА Лобачева… - … вестник психиатрии и …, 2015 - elibrary.ru
Показана большая распространенность больных шизофренией, нуждающихся в
стационарном лечении, в том числе повторно, что является свидетельством тяжести …