[HTML][HTML] Review of the emerging evidence demonstrating the efficacy of ivermectin in the prophylaxis and treatment of COVID-19
Background: After COVID-19 emerged on US shores, providers began reviewing the
emerging basic science, translational, and clinical data to identify potentially effective …
emerging basic science, translational, and clinical data to identify potentially effective …
[HTML][HTML] Repositioning Ivermectin for Covid-19 treatment: Molecular mechanisms of action against SARS-CoV-2 replication
Ivermectin (IVM) is an FDA approved macrocyclic lactone compound traditionally used to
treat parasitic infestations and has shown to have antiviral potential from previous in-vitro …
treat parasitic infestations and has shown to have antiviral potential from previous in-vitro …
[HTML][HTML] Misleading clinical evidence and systematic reviews on ivermectin for COVID-19
Since WHO declared the COVID-19 as a pandemic, 1 2 healthcare systems all over the
world have focused their efforts on limiting the spread of SARS-CoV-2, and despite the …
world have focused their efforts on limiting the spread of SARS-CoV-2, and despite the …
[HTML][HTML] RETRACTED: use of ivermectin in the treatment of Covid-19: a pilot trial
H Pott-Junior, MMB Paoliello, AQC Miguel… - 2021 - Elsevier
Objectives In this randomized open-label trial pilot study we assessed the antiviral effects
and safety of various doses of ivermectin in patients with mild clinical symptoms of COVID …
and safety of various doses of ivermectin in patients with mild clinical symptoms of COVID …
COVID-19 and the promise of small molecule therapeutics: Are there lessons to be learnt?
WS Ho, R Zhang, YL Tan, CLL Chai - Pharmacological Research, 2022 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic had grounded the world to a
standstill. As the disease continues to rage two years on, it is apparent that effective …
standstill. As the disease continues to rage two years on, it is apparent that effective …
Repurposing of FDA-approved drugs as potential inhibitors of the SARS-CoV-2 main protease: Molecular insights into improved therapeutic discovery
With numerous infections and fatalities, COVID-19 has wreaked havoc around the globe.
The main protease (Mpro), which cleaves the polyprotein to form non-structural proteins …
The main protease (Mpro), which cleaves the polyprotein to form non-structural proteins …
Designing AbhiSCoVac-A single potential vaccine for all 'corona culprits': Immunoinformatics and immune simulation approaches
The coronaviridae family has generated highly virulent viruses, including the ones
responsible for three major pandemics in last two decades with SARS in 2002, MERS …
responsible for three major pandemics in last two decades with SARS in 2002, MERS …
[HTML][HTML] Designing efficient multi-epitope peptide-based vaccine by targeting the antioxidant thioredoxin of bancroftian filarial parasite
Thioredoxin is a low molecular weight redox-active protein of filarial parasite that plays a
crucial role in downregulating the host immune response to prolong the survival of the …
crucial role in downregulating the host immune response to prolong the survival of the …
Repurposing ivermectin for COVID-19: Molecular aspects and therapeutic possibilities
As of January 2021, SARS-CoV-2 has killed over 2 million individuals across the world. As
such, there is an urgent need for vaccines and therapeutics to reduce the burden of COVID …
such, there is an urgent need for vaccines and therapeutics to reduce the burden of COVID …
Reverse vaccinology assisted design of a novel multi-epitope vaccine to target Wuchereria bancrofti cystatin: An immunoinformatics approach
Proteases are the critical mediators of immunomodulation exerted by the filarial parasites to
bypass and divert host immunity. Cystatin is a small (∼ 15 kDa) immunomodulatory filarial …
bypass and divert host immunity. Cystatin is a small (∼ 15 kDa) immunomodulatory filarial …