Cisplatin and other platinum-based chemotherapeutic drugs have been used extensively for
the treatment of human cancers such as bladder, blood, breast, cervical, esophageal, head …

Cisplatin is one of the most commonly used anticancer drugs worldwide. It is mainly used in
the treatment of ovarian cancer, but also used in testicular, bladder and lung cancers. The …

While the distant organ environment is known to support metastasis of primary tumors, its
metabolic roles in this process remain underdetermined. Here, in breast cancer models, we …

Cisplatin spearheads the anticancer chemotherapeutics in present-day use although acute
toxicity is its primary impediment factor. Among a plethora of experimental medications, a …

Exosomes are small phospholipid bilayer vesicles that are naturally produced by all living
cells, both prokaryotes and eukaryotes. The exosomes due to their unique size, reduced …

Countless expectations converge in the multidisciplinary endeavour for the search and
development of effective and safe drugs in fighting cancer. Although they still embody a …

Platinum-based chemotherapeutic agents cisplatin and carboplatin are widely used in
cancer treatment worldwide and may result in ototoxic hearing loss. The high incidence of …

Up to seventy-five percent of patients treated for cancer suffer from cognitive deficits which
can persist for months to decades, severely impairing quality of life. Although the number of …

The application of metal compounds in the medical field dates back to the XVI century with
some isolated reports about the therapeutic importance of metals and their compounds in …

Single-cell multiparameter measurement has been increasingly recognized as a key
technology toward systematic understandings of complex molecular and cellular functions in …