Solid lipid nanoparticles and nanostructured lipid carriers: A review emphasizing on particle structure and drug release

A Gordillo-Galeano, CE Mora-Huertas - European Journal of Pharmaceutics …, 2018 - Elsevier
Colloidal systems based on lipids have attracted attention during the last two decades as a
delivery method of drugs that are poorly soluble in water. The investigations carried out have …

Nanotechnology-based drug delivery systems for the treatment of Alzheimer's disease

B Fonseca-Santos, MPD Gremião… - International Journal of …, 2015 - Taylor & Francis
Alzheimer's disease is a neurological disorder that results in cognitive and behavioral
impairment. Conventional treatment strategies, such as acetylcholinesterase inhibitor drugs …

Optimization of nanostructured lipid carriers: Understanding the types, designs, and parameters in the process of formulations

B Subramaniam, ZH Siddik, NH Nagoor - Journal of nanoparticle research, 2020 - Springer
Lipid-based nanoparticles for drug delivery have been employed in the development of
nanomedicine for various applications. One such versatile nanoparticle type is …

[HTML][HTML] Solid lipid nanoparticles for nose to brain delivery of haloperidol: in vitro drug release and pharmacokinetics evaluation

M Yasir, UVS Sara - Acta Pharmaceutica Sinica B, 2014 - Elsevier
In the present study, haloperidol (HP)-loaded solid lipid nanoparticles (SLNs) were prepared
to enhance the uptake of HP to brain via intranasal (in) delivery. SLNs were prepared by a …

Solid lipid nanoparticles for nose to brain delivery of donepezil: formulation, optimization by Box–Behnken design, in vitro and in vivo evaluation

M Yasir, UVS Sara, I Chauhan, PK Gaur… - Artificial cells …, 2018 - Taylor & Francis
This study was aimed at preparing and characterizing solid lipid nanoparticles (SLNs) of
donepezil (DPL) for delivery to brain via nasal route. SLNs were prepared by solvent …

Buspirone loaded solid lipid nanoparticles for amplification of nose to brain efficacy: Formulation development, optimization by Box-Behnken design, in-vitro …

M Yasir, I Chauhan, A Zafar, M Verma… - Journal of Drug Delivery …, 2021 - Elsevier
The strategies to avoid blood brain barrier are been explored to improve brain targeting
therapeutics in order to ensure potential prospects of nose to brain delivery. In this research …

Solid lipid nanoparticles as an efficient drug delivery system of olmesartan medoxomil for the treatment of hypertension

NT Pandya, P Jani, J Vanza, H Tandel - Colloids and surfaces B …, 2018 - Elsevier
The aim of the current investigation was to develop solid lipid nanoparticles of olmesartan
medoxomil using hot homogenization method to improve its oral bioavailability. Central …

An emerging technology in lipid research for targeting hydrophilic drugs to the skin in the treatment of hyperpigmentation disorders: kojic acid-solid lipid nanoparticles

K Khezri, M Saeedi, K Morteza-Semnani… - Artificial cells …, 2020 - Taylor & Francis
Kojic acid (KA) as tyrosinase inhibitor shows insufficient skin penetration and several
adverse events due topical administration. KA solid lipid nanoparticles (KA-SLNs) were …

Fabrication, characterization and optimization of nanostructured lipid carrier formulations using Beclomethasone dipropionate for pulmonary drug delivery via medical …

I Khan, S Hussein, C Houacine, SK Sadozai… - International Journal of …, 2021 - Elsevier
Aerosolization is a non-invasive approach in drug delivery for localized and systemic effect.
Nanostructured lipid carriers (NLCs) are new generation versatile carriers, which offer …

Atorvastatin-based nanoparticle-decorated glyceryl monostearate as a targeted drug carrier for inhibition of atherosclerosis lesions

SK Yadav, K Karthik, M Mahadevappa… - New Journal of …, 2024 - pubs.rsc.org
Macrophages play a significant role in various phases of a chronic atherosclerotic plaque of
the arterial wall. Oxidized low-density lipoprotein (Ox-LDL) accumulation in the tunica intima …