After the hurricane: Anti-COVID-19 drugs development, molecular mechanisms of action and future perspectives

HO Khalifa, YM Al Ramahi - International Journal of Molecular Sciences, 2024 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a new coronavirus in
the Coronaviridae family. The COVID-19 pandemic, caused by SARS-CoV-2, has …

Early detection of SARS-CoV-2 with functionalized gold and molecularly imprinted polymeric nanoparticles: a mini review

P Singla, H Kaur, S Garg, N Kaur… - … Systems Design & …, 2023 - pubs.rsc.org
The novel coronavirus COVID-19 was first reported in Wuhan, China, in December 2019
and rapidly spread to the rest of the world, with the WHO declaring a global pandemic in …

An ultrasensitive and specific fluorescence split-aptasensor for VEGF165 detection based on nicking enzyme-assisted 3D DNA walker coupling with CRISPR-Cas12a

B Xiong, X Li, Y Zhang, C Yan, G Wang - Spectrochimica Acta Part A …, 2025 - Elsevier
The overexpression of vascular endothelial growth factor 165 (VEGF 165) in cancer cells
plays a pivotal role in promoting tumor metastasis by facilitating their excessively rapid …

Aptamer-decorated nanocarriers for viral adsorption: A special look at COVID-19

S Handali, M Rezaei - Molecular Therapy-Nucleic Acids, 2024 - cell.com
Viral infections are one of the leading causes of death in the world. One main challenge in
fighting against these diseases is the unavailability of effective eradicating drugs and …

[引用][C] Therapeutic Applications of Aptamers

G Santarpia, E Carnes - Int. J. Mol. Sci, 2024 - europepmc.org
Affinity reagents, or target-binding molecules, are quite versatile and are major workhorses
in molecular biology and medicine. Antibodies are the most famous and frequently used …

Enhancement of the signal resolution in aptamer assay upon target binding by employing DNA probes and dual fluorophores

HJ Lim, A Son - Microchemical Journal, 2024 - Elsevier
In this study, we aimed to significantly enhance the resolution of aptamer assays by using
DNA probes and dual fluorophores. The resolution is defined as the smallest change in the …

[HTML][HTML] Emerging perspectives on RNA virus-mediated infections: from pathogenesis to therapeutic interventions

P Mohanty, P Panda, RK Acharya, B Pande… - World Journal of …, 2023 - ncbi.nlm.nih.gov
RNA viruses continue to pose significant threats to global public health, necessitating a
profound understanding of their pathogenic mechanisms and the development of effective …

Natural Products as Inhibitors of Coronavirus: An Update

R Kalia, A Dey, SM Jachak - Coronaviruses, 2024 - benthamdirect.com
In the past couple of decades, several corona virus infections have alarmed the world
claiming deaths of huge population over the globe. Effective anti-viral agents have been …

Interplay of TLR4 and SARS-CoV-2: unveiling the complex mechanisms of inflammation and severity in COVID-19 infections

CN Asaba, CJ Ekabe, HS Ayuk… - Journal of …, 2024 - Taylor & Francis
The late 2019 emergence of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2), the causative agent of COVID-19, caused profound and unprecedented disruption …

[引用][C] Application of COVID-19 Aptamer for Imparting Antiviral Functionality to Healthcare Product

KIM Hyun, MH PARK, P Ga-Young, SJ RHEE… - 한국생물공학회학술 …, 2023 - dbpia.co.kr
COVID-19 is an infectious disease caused by the SARS-CoV-2 virus, which ravaged the
world starting from late 2019, resulting in widespread suffering. In May 2023, WHO ended …