Cellular plasticity contributes to the regenerative capacity of plants, invertebrates, teleost
fishes and amphibians. In vertebrates, differentiated cells are known to revert into replicating …

Microscopic imaging techniques to visualize cellular behaviors in their natural environment
play a pivotal role in biomedical research. Here, we review how recent technical advances …

Currently, most biological research relies on conventional experimental techniques that
allow only static analyses at certain time points in vitro or ex vivo. However, if one could …

Following injury, stem cells restore normal tissue architecture by producing the proper
number and proportions of differentiated cells. Current models of airway epithelial …

Stem cells integrate inputs from multiple sources. Stem cell niches provide signals that
promote stem cell maintenance,, while differentiated daughter cells are known to provide …

The pseudostratified epithelium of the lung contains ciliated and secretory luminal cells and
basal stem/progenitor cells. To identify signals controlling basal cell behavior we screened …

A conference,“Stem Cells and Cell Therapies in Lung Biology and Lung Diseases,” was
held July 25 to 28, 2011 at the University of Vermont to review the current understanding of …

Intratracheal delivery of stem cells into injured or diseased lungs can provide a variety of
therapeutic and immunomodulatory effects for the treatment of acute lung injury and chronic …

Epididymal development can be subdivided into three phases: undifferentiated, a period of
differentiation, and expansion. The objectives of this study were (1) to assess gene …

Clara cells (CCs) are a morphologically and operationally heterogeneous population of
Secretoglobin Scgb1a1-expressing secretory cells that are crucial for airway homeostasis …