Graves orbitopathy, also known as thyroid eye disease or thyroid-associated orbitopathy, is
visually disabling, cosmetically disfiguring and has a substantial negative impact on a …

Since the 1970s, the role of infectious diseases in the pathogenesis of Graves' disease (GD)
has been an object of intensive research. The last decade has witnessed many studies on …

Background Variation in induced models of autoimmunity has been attributed to the housing
environment and its effect on the gut microbiota. In Graves' disease (GD), autoantibodies to …

Introduction Graves' disease (GD) is an autoimmune disorder caused by autoantibodies
against the thyroid stimulating hormone receptor (TSHR) leading to overstimulation of the …

The effect of selenium supplementation on recurrent hyperthyroidism caused by Graves'
disease is unclear. Our study aimed to assess the efficacy of selenium supplementation …

Experimental models of hyperthyroid Graves' disease (GD) and Graves' orbitopathy (GO) are
efficiently developed by genetic immunisation by electroporation with human thyrotropin …

We recently described a preclinical model of Graves' orbitopathy (GO), induced by genetic
immunization of eukaryotic expression plasmid encoding human TSH receptor (TSHR) A …

Thyroid associated ophthalmopathy (TAO), characterized by T cell infiltration and orbital
fibroblast activation, is an organ-specific autoimmune disease which is still short of effective …

Background: Graves' orbitopathy (GO) is the most common and serious manifestation of
Graves' disease (GD). It is characterized by orbital inflammation and tissue remodeling …

Introduction Graves' disease (GD) is an autoimmune disorder responsible for 60–90% of
thyrotoxicosis, with an incidence of 1 to 2 cases per 1000 population per year in England …