This review compiles information regarding the use of alginate, and in particular alginate
hydrogels, in culturing cells in 3D. Knowledge of alginate chemical structure and …

Polymer scaffolds have many different functions in the field of tissue engineering. They are
applied as space filling agents, as delivery vehicles for bioactive molecules, and as three …

Completely revised and expanded to reflect the latest advancements in the field,
Polysaccharides: Structural Diversity and Functional Versatility, Second Edition outlines …

There has been a consistent increase in the mean life expectancy of the population of the
developed world over the past century. Healthy life expectancy, however, has not increased …

Cancer has become one of the most difficult health challenges of our time, accounting for
millions of deaths yearly. Systemic chemotherapy is the most common therapeutic approach; …

An in vivo model has been established to study the role of macrophages in the initiation of
angiogenesis by human breast tumour spheroids in vivo. The extent of the angiogenic …

Tissue neovascularization involves recruitment of circulating endothelial progenitor cells that
originate in the bone marrow. Here, we show that a class of embryonic endothelial …

Traditional cancer therapy typically targets the tumor proper. However, newly-formed
vasculature exerts a major role in cancer development and progression. Autophagy, as a …

Malignant brain tumors including glioblastoma are incurable cancers. Over the last years a
number of promising novel treatment approaches have been investigated including the …

Brain tumors are characterized by very high mortality and, despite the continuous research
on new pharmacological interventions, little therapeutic progress has been made. One of the …