Nucleophilic aromatic substitution (SNAr) reactions were optimized using high-throughput
experimentation techniques for execution under flow conditions. A total of 3072 unique …

We employed a polymer network to understand what properties of pyrogenic carbonaceous
matter (PCM; eg., activated carbon) confer its reactivity, which we hereinafter referred to as …

A kinetic study is reported for nucleophilic substitution reactions of 2, 4-dinitro-1-
fluorobenzene (DNFB) with a series of secondary amines in MeCN and H2O at 25.0° C. The …

Analogies between the mechanisms of electrophilic substitution and nucleophilic
substitution have been discussed. Theoretical calculations, involving aromaticity …

The reactions of the title compounds with phenoxides, secondary alicyclic (SA) amines, and
pyridines, in 44 wt% ethanol–water, at 25° C and an ionic strength of 0.2 M, were subjected …

We herein report results obtained from an integrated experimental and theoretical study on
aromatic nucleophilic substitution (SNAr) reactions of a series of amines towards 1-fluoro-2 …

Aryl halides containing electron‐withdrawing substituent (s) at ortho and para position
undergoes aromatic nucleophilic substitution reaction with sulfur nucleophile present in …

An experimental and computational methodology for the analysis of the Lewis acid/base
responses of ionic liquids (ILs) and deep eutectic solvents (DES) is proposed. It is based on …

Rate measurements are reported for the reactions of 12 ring‐substituted anilines with 2, 4‐
dinitrophenyl 2, 4, 6‐trinitrophenyl ether (1) in acetonitrile. Formation of the products, the …

Few kinetic parameters, or reaction rates, are known up to date in detail about 1-chloro and
1-fluoro-2, 4-dinitrobenzene (ClDNB and FDNB, respectively) with a series of biothiols in …