Overview of the 2022 WHO classification of adrenal cortical tumors

O Mete, LA Erickson, CC Juhlin, RR de Krijger… - Endocrine …, 2022 - Springer
The new WHO classification of adrenal cortical proliferations reflects translational advances
in the fields of endocrine pathology, oncology and molecular biology. By adopting a …

Diagnosis and treatment of primary aldosteronism

M Reincke, I Bancos, P Mulatero, UI Scholl… - The lancet Diabetes & …, 2021 - thelancet.com
Primary aldosteronism is a common cause of secondary hypertension associated with
excess cardiovascular morbidities. Primary aldosteronism is underdiagnosed because it …

Japan Endocrine Society clinical practice guideline for the diagnosis and management of primary aldosteronism 2021

M Naruse, T Katabami, H Shibata, M Sone… - Endocrine …, 2022 - jstage.jst.go.jp
Primary aldosteronism (PA) is associated with higher cardiovascular morbidity and mortality
rates than essential hypertension. The Japan Endocrine Society (JES) has developed an …

Primary aldosteronism—a multidimensional syndrome

AF Turcu, J Yang, A Vaidya - Nature Reviews Endocrinology, 2022 - nature.com
Primary aldosteronism is a common cause of hypertension and is a risk factor for
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …

Primary aldosteronism: state-of-the-art review

A Vaidya, GL Hundemer, K Nanba… - American Journal of …, 2022 - academic.oup.com
We are witnessing a revolution in our understanding of primary aldosteronism (PA). In the
past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …

[11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial

X Wu, R Senanayake, E Goodchild, WA Bashari… - Nature Medicine, 2023 - nature.com
Primary aldosteronism (PA) due to a unilateral aldosterone-producing adenoma is a
common cause of hypertension. This can be cured, or greatly improved, by adrenal surgery …

Somatic SLC30A1 mutations altering zinc transporter ZnT1 cause aldosterone-producing adenomas and primary aldosteronism

J Rege, S Bandulik, K Nanba, C Kosmann… - Nature Genetics, 2023 - nature.com
Primary aldosteronism (PA) is the most common form of endocrine hypertension and is
characterized by inappropriately elevated aldosterone production via a renin-independent …

Genetics of primary aldosteronism

UI Scholl - Hypertension, 2022 - Am Heart Assoc
Primary aldosteronism is considered the commonest cause of secondary hypertension. In
affected individuals, aldosterone is produced in an at least partially autonomous fashion in …

The saline infusion test for primary aldosteronism: implications of immunoassay inaccuracy

G Eisenhofer, M Kurlbaum, M Peitzsch… - The Journal of …, 2022 - academic.oup.com
Context Diagnosis of primary aldosteronism (PA) for many patients depends on positive
results for the saline infusion test (SIT). Plasma aldosterone is often measured by …

Biomarkers to guide medical therapy in primary aldosteronism

GL Hundemer, AA Leung, GA Kline… - Endocrine …, 2024 - academic.oup.com
Primary aldosteronism (PA) is an endocrinopathy characterized by dysregulated
aldosterone production that occurs despite suppression of renin and angiotensin II, and that …