Various biological attributes associated with individual fitness in animals change predictably over the lifespan of an organism. Therefore, the study of animal ecology and the work of …
N Beying, C Schmidt, M Pacher, A Houben, H Puchta - Nature plants, 2020 - nature.com
Clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated protein (Cas) technology has been applied in plant breeding mainly on genes for improving …
P Frit, N Barboule, Y Yuan, D Gomez, P Calsou - DNA repair, 2014 - Elsevier
To cope with DNA double strand break (DSB) genotoxicity, cells have evolved two main repair pathways: homologous recombination which uses homologous DNA sequences as …
Infertility affects one in six couples worldwide, and fertility continues to deteriorate globally, partly owing to a decline in semen quality. Sperm analysis has a central role in diagnosing …
M Rönspies, P Schindele, R Wetzel, H Puchta - Nature Protocols, 2022 - nature.com
The rise of the clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR- associated protein (Cas) system has made it possible to induce double-strand breaks at …
The model for telomere shortening at each replication cycle is currently incomplete, and the exact contribution of the telomeric 3′ overhang to the shortening rate remains unclear …
The evolutionary and ecological success of spermatophytes is intrinsically linked to the seed habit, which provides a protective environment for the initial development of the new …
K Cleal, K Norris, D Baird - International Journal of Molecular Sciences, 2018 - mdpi.com
Telomeres are progressively eroded during repeated rounds of cell division due to the end replication problem but also undergo additional more substantial stochastic shortening …
P Procházková Schrumpfová, M Fojtová, J Fajkus - Cells, 2019 - mdpi.com
Parallel research on multiple model organisms shows that while some principles of telomere biology are conserved among all eukaryotic kingdoms, we also find some deviations that …