Tetrazole: A privileged scaffold for the discovery of anticancer agents

A Verma, B Kaur, S Venugopal… - Chemical Biology & …, 2022 - Wiley Online Library
Carcinoma, characterized by abnormal growth of cells and tissue, is a ubiquitously leading
cause of mortality across the globe due to some carcinogenic factors. Currently, several …

Hetero-bimetallic cooperative catalysis for the synthesis of heteroarenes

GR Gupta, J Shah, KS Vadagaonkar… - Organic & …, 2019 - pubs.rsc.org
Multi-metallic cooperative catalysis has gained a lot of interest in organic synthesis over the
past few years exploring various organic transformations. Of all the myriad chemical …

Sequential Pd (0)/Fe (III) catalyzed azide–isocyanide coupling/cyclization reaction: One-pot synthesis of aminotetrazoles

RS Pathare, AJ Ansari, S Verma… - The Journal of …, 2018 - ACS Publications
A rapid and efficient synthesis of aminotetrazole from aryl azides, isocyanides, and TMSN3
is developed. The reaction is promoted by sequential Pd (0)/Fe (III) catalysis. The reaction …

Pd (II)-catalyzed aminotetrazole-directed ortho-selective halogenation of arenes

P Sadhu, SK Alla, T Punniyamurthy - The Journal of Organic …, 2013 - ACS Publications
A Pd (II)-catalyzed ortho-selective halogenation of N-aryl ring of N, 1-diaryl-1 H-tetrazol-5-
amine has been described employing N-halosuccinimide as a halogen source via C–H …

Domino N2-Extrusion–Cyclization of Alkynylarylketone Derivatives for the Synthesis of Indoloquinolines and Carbocycle-Fused Quinolines

B Akkachairin, J Tummatorn… - The Journal of …, 2018 - ACS Publications
New synthetic approaches for the synthesis of indoloquinolines and carbocycle-fused
quinolines have been developed employing alkynylketone substrates. These synthetic …

An eco-friendly water mediated synthesis of 1, 2, 3-triazolyl-2-aminopyrimidine hybrids as highly potent anti-bacterial agents

S Nagarajan, P Shanmugavelan, M Sathishkumar… - Chinese Chemical …, 2014 - Elsevier
An elegant and efficient synthesis of novel 1, 2, 3-triazole fused 2-aminopyrimidine hybrids
has been accomplished for the first time in the green solvent viz. water. The hybrid …

Recent advances in the multicomponent synthesis of heterocycles using 5-aminotetrazole

R Javahershenas, H Mei, M Koley, VA Soloshonok… - …, 2024 - thieme-connect.com
The unique reactivity and beneficial features of the 5-aminotetrazole synthon (1H-tetrazol-5-
amine) have made it a versatile and effective building block in the synthesis of heterocyclic …

Multicomponent cyclization with azides to synthesize N-heterocycles

H Guo, B Zhou, J Chang, W Chang, J Feng… - Organic & Biomolecular …, 2023 - pubs.rsc.org
Heterocyclic compounds, both naturally derived and synthetically produced, constitute a
wide variety of biologically active and industrially important compounds. The synthesis and …

Three-Component Synthesis of 1-Substituted 5-Aminotetrazoles Promoted by Bismuth Nitrate

IS de Jesus, A Trindade Gomes, I Sande… - The Journal of Organic …, 2024 - ACS Publications
A nontoxic bismuth-promoted multicomponent synthesis of 5-aminotetrazoles and
bistetrazoles is reported. The reaction of phenyl isothiocyanate, NaN3, and amine (primary …

An efficient method for the synthesis of substituted 5-aminotetrazoles from selenoureas using PhI (OAc) 2

Y Xie, D Guo, X Jiang, H Pan, W Wang, T Jin, Z Mi - Tetrahedron Letters, 2015 - Elsevier
An efficient method to access 5-aminotetrazoles starting from readily accessible 1, 3-
disubtituted selenoureas has been discovered. This is the first example of the synthesis of 5 …