Obesity and bone: a complex relationship

G Rinonapoli, V Pace, C Ruggiero, P Ceccarini… - International journal of …, 2021 - mdpi.com
There is a large literature on the relationship between obesity and bone. What we can
conclude from this review is that the increase in body weight causes an increase in BMD …

Epidemiology of fracture risk with advancing age

KE Ensrud - Journals of Gerontology Series A: Biomedical …, 2013 - academic.oup.com
Bone loss and structural damage with advancing age lead to skeletal fragility as manifested
by low bone mass and deficits in bone geometry, microarchitecture, and material properties …

Association of the magnitude of weight loss and changes in physical fitness with long-term cardiovascular disease outcomes in overweight or obese people with type …

Look AHEAD Research Group - The lancet Diabetes & endocrinology, 2016 - Elsevier
Summary Background Findings from the Look AHEAD trial showed no significant reductions
in the primary outcome of cardiovascular disease incidence in adults with type 2 diabetes …

Comparison of 2 frailty indexes for prediction of falls, disability, fractures, and death in older women

KE Ensrud, SK Ewing, BC Taylor, HA Fink… - Archives of internal …, 2008 - jamanetwork.com
Background Frailty, as defined by the index derived from the Cardiovascular Health Study
(CHS index), predicts risk of adverse outcomes in older adults. Use of this index, however, is …

[HTML][HTML] Appetite assessment: simple appetite questionnaire predicts weight loss in community-dwelling adults and nursing home residents

MMG Wilson, DR Thomas, LZ Rubenstein… - The American journal of …, 2005 - Elsevier
Background: Anorexia-related weight loss can have devastating consequences on quality-of-
life, morbidity, and mortality. Without a simple tool to evaluate appetite, health care providers …

A comparison of frailty indexes for the prediction of falls, disability, fractures, and mortality in older men

KE Ensrud, SK Ewing, PM Cawthon… - Journal of the …, 2009 - Wiley Online Library
OBJECTIVES: To compare the validity of a parsimonious frailty index (components: weight
loss, inability to rise from a chair, and poor energy (Study of Osteoporotic Fractures (SOF) …

Type 2 diabetes mellitus and bone

J Compston - Journal of internal medicine, 2018 - Wiley Online Library
Abstract Type 2 diabetes (T2 DM) is a rapidly growing public health problem. It is associated
with an increased risk of fracture, particularly of the hip, despite normal or high bone mineral …

Interrelationship among muscle, fat, and bone: connecting the dots on cellular, hormonal, and whole body levels

JZ Ilich, OJ Kelly, JE Inglis, LB Panton, G Duque… - Ageing research …, 2014 - Elsevier
While sarcopenia and sarcopenic obesity have been recognized in the last decade, a
combined concept to include decreased muscle mass and strength, as well as decreased …

Marrow fat and bone: review of clinical findings

AV Schwartz - Frontiers in endocrinology, 2015 - frontiersin.org
With growing interest in the connection between fat and bone, there has been increased
investigation of the relationship with marrow fat in particular. Clinical research has been …

The definition of weight maintenance

J Stevens, KP Truesdale, JE McClain… - International journal of …, 2006 - nature.com
There is currently no consensus on the definition of weight maintenance in adults. Issues to
consider in setting a standard definition include expert opinion, precedents set in previous …