Nanoparticle amplification labeling for high-performance magnetic cell sorting

Z Wang, H Wang, S Lin, S Ahmed, S Angers… - Nano …, 2022 - ACS Publications
Magnetic cell sorting is an enabling tool for the isolation of specific cellular subpopulations
for downstream applications and requires the cells to be labeled by a sufficient number of …

Micro-magnetofluidic system for rare cell analysis: from principle to translation

K Chen, Z Wang - Chemosensors, 2023 - mdpi.com
Rare cells play essential roles in the initiation and progression of diseases and therefore
their analysis is of great interest. The micro-magnetofluidic system is one of the emerging …

Defining and targeting tumor-associated macrophages in malignant mesothelioma

L Wu, M Kohno, J Murakami, A Zia… - Proceedings of the …, 2023 - National Acad Sciences
Defining the ontogeny of tumor-associated macrophages (TAM) is important to develop
therapeutic targets for mesothelioma. We identified two distinct macrophage populations in …

Liquid biopsy: paving a new avenue for cancer research

K Kurma, Z Eslami-S, C Alix-Panabières… - Cell Adhesion & …, 2024 - Taylor & Francis
The current constraints associated with cancer diagnosis and molecular profiling, which rely
on invasive tissue biopsies or clinical imaging, have spurred the emergence of the liquid …

Genome-wide in vivo screen of circulating tumor cells identifies SLIT2 as a regulator of metastasis

F Xia, Y Ma, K Chen, B Duong, S Ahmed, R Atwal… - Science …, 2022 - science.org
Circulating tumor cells (CTCs) break free from primary tumors and travel through the
circulation system to seed metastatic tumors, which are the major cause of death from …

[HTML][HTML] Tumor-infiltrating lymphocytes are functionally inactivated by CD90+ stromal cells and reactivated by combined Ibrutinib and Rapamycin in human pleural …

H Yang, S Berezowska, P Dorn, P Zens, P Chen… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Despite evidence suggesting that the tumor microenvironment (TME) in
malignant pleural mesothelioma (MPM) is linked with poor prognosis, there is a lack of …

[HTML][HTML] Diagnosis of Pleural Mesothelioma: Is Everything Solved at the Present Time?

E Roca, A Aujayeb, P Astoul - Current Oncology, 2024 - mdpi.com
Ranked high in worldwide growing health issues, pleural diseases affect approximately one
million people globally per year and are often correlated with a poor prognosis. Among …

A magneto-activated nanoscale cytometry platform for molecular profiling of small extracellular vesicles

K Chen, BTV Duong, SU Ahmed, P Dhavarasa… - Nature …, 2023 - nature.com
Abstract Exosomal PD-L1 (exoPD-L1) has recently received significant attention as a
biomarker predicting immunotherapeutic responses involving the PD1/PD-L1 pathway …

Phenotypic Screening of Rare Tumor Cells Using Microfluidic Platforms

F Xia - 2021 - search.proquest.com
Metastatic disease accounts for 90% deaths from cancer. As rare tumor cells shed from
primary tumors, circulating tumor cells (CTCs) are considered as “seeds” of secondary …

Microsystem Technology for Next-generation Cellular Therapy

Z Wang - 2022 - search.proquest.com
Cellular therapy is a treatment where viable cells are injected or grafted into a patient in
order to generate therapeutic effects, such as grafting stem cells to regenerate damaged …