Thalassemias in South Asia: clinical lessons learnt from Bangladesh

MS Hossain, E Raheem, TA Sultana, S Ferdous… - Orphanet journal of rare …, 2017 - Springer
Thalassemias are emerging as a global public health concern. Due to remarkable success
in the reduction of childhood mortality by controlling infectious diseases in developing …

[HTML][HTML] Prevalence of Transfusion Transmissible Infections in Beta-Thalassemia Major Patients of Pakistan: A Systematic Review

H Ehsan, A Wahab, MA Shafqat, MS Faisal, A Muneeb… - Blood, 2020 - Elsevier
Introduction: β-thalassemia major (TM) is one of the most prevalent inherited
hemoglobinopathies in Pakistan. It has one of the highest prevalence of transfusion …

Anthropometric measurements in children having transfusion-dependent beta thalassemia

B Moiz, A Habib, S Sawani, A Raheem, B Hasan… - …, 2018 - Taylor & Francis
Objectives: The aim of this study was to determine the anthropometric measurements in
transfusion-dependent β-thalassemia children in Pakistan. The secondary aim was to …

Novel genetic therapeutic approaches for modulating the severity of β‑thalassemia

F Amjad, T Fatima, T Fayyaz… - Biomedical …, 2020 - spandidos-publications.com
Thalassemia is a genetic haematological disorder that arises due to defects in the α and β‑
globin genes. Worldwide, 0.3‑0.4 million children are born with haemoglobinopathies per …

[HTML][HTML] Malnutrition, its attributes, and impact on quality of life: an epidemiological study among β-thalassemia major children

B Biswas, NN Naskar, K Basu, A Dasgupta… - Korean Journal of …, 2021 - ncbi.nlm.nih.gov
Background India is home to a large number of thalassemic children. Despite malnutrition
being an essential determinant of their therapeutic goals and quality of life (QoL), it was …

[PDF][PDF] Keeping it in the family: consanguineous marriage and genetic disorders, from Islamabad to Bradford

M Merten - Bmj, 2019 - researchgate.net
One billion people worldwide live in countries where marriage among relatives is common.
Of this billion, one in three is married to a second cousin or closer relative or is the progeny …

Implementation of public health genomics in Pakistan

M Riaz, J Tiller, M Ajmal, M Azam, R Qamar… - European Journal of …, 2019 - nature.com
There has been considerable recent progress in the implementation of public health
genomics policy throughout the developed world. However, in the developing world, genetic …

[PDF][PDF] Mutational analysis of beta thalassaemia by multiplex ARMS-PCR in Khyber Pakhtunkhwa, Pakistan

T Jalil, YM Yousafzai, I Rashid… - Journal of Ayub …, 2019 - demo.ayubmed.edu.pk
Background: Beta thalassaemia is one of the commonest genetic condition in the world.
More than 200 different mutations have been reported in the beta globin chain genes …

[PDF][PDF] Evaluation of five discriminating indexes to distinguish Beta-Thalassemia Trait from Iron Deficiency Anaemia

Z Ullah, AA Khattak, SA Ali, J Hussain, B Noor… - J Pak Med …, 2016 - researchgate.net
Objective: To assess the reliability of different red blood cell indices-based formulae in the
indexes formula in differential diagnosis of beta thalassemia trait and iron deficiency …

Beta thalassemia-a review

R Jha, S Jha - Journal of pathology of Nepal, 2014 - nepjol.info
Thalassemia is a globin gene disorder that results in a diminished rate of synthesis of one or
more of the globin chains. About 1.5% of the global population (80 to 90 million people) are …