Alzheimer’s disease as a chronic maladaptive polyamine stress response - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main …
E Roda, F De Luca, D Ratto, EC Priori, E Savino… - Biology, 2023 - mdpi.com
Simple Summary With the increase in the geriatric population worldwide, the promotion of healthy aging arose as a key issue and, hence, the scientific community dedicates huge …
F Scialo, A Sanz - Free Radical Biology and Medicine, 2021 - Elsevier
Mitochondria are the powerhouses of the cell. They produce a significant amount of the energy we need to grow, survive and reproduce. The same system that generates energy in …
Pulmonary fibrosis (PF) is an epithelial/fibroblastic crosstalk disorder of the lungs with highly complex etiopathogenesis. Limited treatment possibilities are responsible for poor prognosis …
A Elgaabari, N Imatomi, H Kido, T Nakashima… - Aging cell, 2024 - Wiley Online Library
Mechanical perturbation triggers activation of resident myogenic stem cells to enter the cell cycle through a cascade of events including hepatocyte growth factor (HGF) release from its …
Bone metastatic prostate cancer (BM-PCa) remains one of the most difficult cancers to treat due to the complex interactions of cancer and stromal cells. We previously showed that bone …
A Garate-Carrillo, V Navarrete-Yañez… - European journal of …, 2020 - Elsevier
Endothelial dysfunction (EnD) occurs with aging and endothelial nitric oxide (NO) production by NO synthase (NOS) can be impaired. Low NO levels have been linked to increased …
T Gori - International Journal of Molecular Sciences, 2020 - mdpi.com
Amyl nitrite was introduced in 1867 as the first molecule of a new class of agents for the treatment of angina pectoris. In the following 150 years, the nitric oxide pathway has been …
N Kurhaluk - Nutrition Reviews, 2023 - academic.oup.com
Ageing is a natural ontogenetic phenomenon that entails a decrease in the adaptive capacity of the organism, as a result of which the body becomes less adaptable to stressful …