Antibodies can impact pathogens in the presence or in the absence of effector cells or
effector molecules such as complement, and experiments can often sort out with precision …

Immunosuppression due to therapy after transplantation or associated with HIV infection
increases susceptibility to various central nervous system (CNS) infections. This article …

Millions of people worldwide are infected with filarial nematodes, responsible for lymphatic
filariasis (LF) and other diseases causing chronic disablement. Elimination programs have …

Helminths are master regulators of host immune responses utilising complex mechanisms to
dampen host protective Th2‐type responses and favour long‐term persistence. Such …

In order to understand natural resistance to filariasis, we compared Litomosoides
sigmodontis primary infection of C57BL/6 mice, which eliminate the worms before patency …

Background: There is compelling evidence that not only do anti-filarials significantly reduce
larval forms, but that host immune responses also contribute to the clearance of filarial …

Filarial infections remain a major public health and socio‐economic problem across the
tropics, despite considerable effort to reduce disease burden or regionally eliminate the …

Lymphatic filariasis, a mosquito‐borne parasitic disease, affects more than 120 million
people worldwide. Vaccination for filariasis by targeting different stages of the parasite will …

Secretion of immunomodulatory molecules is a key strategy employed by pathogens to
enable their survival in host organisms. For example, arthropod‐transmitted filarial …

Helminth parasites are known to be efficient modulators of their host's immune system. To
guarantee their own survival, they induce alongside the classical Th2 a strong regulatory …