Sex bias in lymphocytes: Implications for autoimmune diseases

KC Dodd, M Menon - Frontiers in Immunology, 2022 - frontiersin.org
Autoimmune diseases are characterized by a significant sex dimorphism, with women
showing increased susceptibility to disease. This is, at least in part, due to sex-dependent …

Pharmacogenomics of monoclonal antibodies for the treatment of rheumatoid arthritis

SH Lim, K Kim, CI Choi - Journal of Personalized Medicine, 2022 - mdpi.com
Precision medicine refers to a highly individualized and personalized approach to patient
care. Pharmacogenomics is the study of how an individual's genomic profile affects their …

Development of dexibuprofen loaded nano transfersomal gel with enhanced biopharmaceutical performance in complete Freund's adjuvant induced arthritis model

M Rafique, Z Ali, S Sohail, F Zahid, MI Khan… - Journal of Drug Delivery …, 2024 - Elsevier
The purpose of this study was to enhance the biopharmaceutical performance of
Dexibuprofen (DXI) using transfersomal gel (DXI-TG) as drug delivery system. DXI loaded …

Combined repetitive inhalant endotoxin and collagen-induced arthritis drive inflammatory lung disease and arthritis severity in a testosterone-dependent manner

JA Poole, GM Thiele, E Ramler… - … of Physiology-Lung …, 2024 - journals.physiology.org
Respiratory-related diseases are a leading cause of death in rheumatoid arthritis (RA) and
are disproportionately higher in men, which may be attributable to environmental risk factors …

Tailoring rheumatoid arthritis treatment through a sex and gender lens

L Carmona, E Aurrecoechea… - Journal of Clinical …, 2023 - mdpi.com
Rheumatoid arthritis (RA) occurs more frequently in women than in men, and the studies that
have addressed clinical and prognostic differences between the sexes are scarce and have …

[HTML][HTML] Gut Microbiota Modulation: A Novel Strategy for Rheumatoid Arthritis Therapy

V Chasov, E Gilyazova, I Ganeeva, E Zmievskaya… - Biomolecules, 2024 - mdpi.com
Rheumatoid arthritis (RA) is a chronic autoimmune disease that leads to joint inflammation,
progressive tissue damage and significant disability, severely impacting patients' quality of …

Sex-Specific Protection of Endothelial Function after Vascular Ischemia/Reperfusion Injury by the Senomorphic Agent Ruxolitinib

L Saemann, P Naujoks, L Hartrumpf, S Pohl… - International Journal of …, 2023 - mdpi.com
Ischemia/reperfusion (I/R)-induced endothelial dysfunction occurs in various cardiovascular
disorders. I/R injury is partially driven by the release of cytokines. Known for its use in …

[HTML][HTML] Sex-oriented perspectives in immunopharmacology

A Cignarella, E Vegeto, C Bolego, L Trabace… - Pharmacological …, 2023 - Elsevier
Several immunopharmacological agents are effective in the treatment of cancer and immune-
mediated conditions, with a favorable impact on life expectancy and clinical outcomes for a …

Sex differences in the benefit of tea consumption: a critical summation of the epidemiological evidence

C He, P Ye, X Zhang, Y Li, Q Li, P Lü, C Cai, X Cai - Food Bioscience, 2024 - Elsevier
Tea is acknowledged by the US Food and Drug Administration (FDA) as an important
functional food, and is classified as 'Generally Recognized as Safe'(GRAS). Extensive …

Autoimmune thyroid disease and rheumatoid arthritis: where the twain meet

A Lichtiger, G Fadaei, CE Tagoe - Clinical Rheumatology, 2024 - Springer
Autoimmune thyroid disease (AITD) is the most prevalent autoimmune disease. It shares
multiple genetic, clinical, and serologic characteristics with rheumatoid arthritis (RA) …