Chemical and biophysical signatures of the protein corona in nanomedicine

J Ren, N Andrikopoulos, K Velonia… - Journal of the …, 2022 - ACS Publications
An inconvenient hurdle in the practice of nanomedicine is the protein corona, a spontaneous
collection of biomolecular species by nanoparticles in living systems. The protein corona is …

Carbohydrate-based macromolecular biomaterials

L Su, Y Feng, K Wei, X Xu, R Liu, G Chen - Chemical Reviews, 2021 - ACS Publications
Carbohydrates are the most abundant and one of the most important biomacromolecules in
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …

The effects of protein corona on in vivo fate of nanocarriers

Q Xiao, M Zoulikha, M Qiu, C Teng, C Lin, X Li… - Advanced Drug Delivery …, 2022 - Elsevier
With the emerging advances in utilizing nanocarriers for biomedical applications, a
molecular-level understanding of the in vivo fate of nanocarriers is necessary. After …

The protein corona and its effects on nanoparticle-based drug delivery systems

H Li, Y Wang, Q Tang, D Yin, C Tang, E He, L Zou… - Acta biomaterialia, 2021 - Elsevier
In most cases, once nanoparticles (NPs) enter the blood, their surface is covered by
biological molecules, especially proteins, forming a so-called protein corona (PC). As a …

Influence of surface chemistry and morphology of nanoparticles on protein corona formation

R Bilardo, F Traldi, A Vdovchenko… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Nanomaterials offer promising solutions as drug delivery systems and imaging agents in
response to the demand for better therapeutics and diagnostics. However, the limited …

Bioinspired nanotopographical design of drug delivery systems

JA Finbloom, C Huynh, X Huang… - Nature Reviews …, 2023 - nature.com
Effective drug delivery is important in the treatment of various biomedical conditions, ranging
from autoimmune disorders to cancer and bacterial infections. Nanostructured systems can …

How nanoparticles open the paracellular route of biological barriers: mechanisms, applications, and prospects

J Wu, Z Zhu, W Liu, Y Zhang, Y Kang, J Liu, C Hu… - ACS …, 2022 - ACS Publications
Biological barriers are essential physiological protective systems and obstacles to drug
delivery. Nanoparticles (NPs) can access the paracellular route of biological barriers, either …

The role of protein corona on nanodrugs for organ-targeting and its prospects of application

S Wang, J Zhang, H Zhou, YC Lu, X Jin, L Luo… - Journal of Controlled …, 2023 - Elsevier
Nowadays, nanodrugs become a hotspot in the high-end medical field. They have the ability
to deliver drugs to reach their destination more effectively due to their unique properties and …

Polymer-functionalized upconversion nanoparticles for light/imaging-guided drug delivery

L Zhang, D Jin, MH Stenzel - Biomacromolecules, 2021 - ACS Publications
The strong upconversion luminescence (UCL) of upconversion nanoparticles (UCNPs)
endows the nanoparticles with attractive features for combined imaging and drug delivery …

Glycopolymers for drug delivery: opportunities and challenges

MH Stenzel - Macromolecules, 2022 - ACS Publications
Glycopolymers are synthetic polymers with pendant sugars, which hold promise for a range
of biomedical applications ranging from tissue engineering to sensing. The known specific …