Cells respond to and actively remodel the extracellular matrix (ECM). The dynamic and
bidirectional interaction between cells and ECM, especially their mechanical interactions …

Tendon, ligament, and skeletal muscle are highly organized tissues that largely rely on a
hierarchical collagenous matrix to withstand high tensile loads experienced in activities of …

Purpose Collagen peptide supplementation has been reported to enhance synthesis rates
or growth in a range of musculoskeletal tissues and could enhance tendinous tissue …

Tendon mechanobiology plays a vital role in tendon repair and regeneration; however, this
mechanism is currently poorly understood. We tested the role of different mechanical loads …

The Ehlers-Danlos syndromes (EDS) are a group of 13 disorders, clinically defined through
features of joint hypermobility, skin hyperextensibility, and tissue fragility. Most subtypes are …

Tendon cells exist in a dense extracellular matrix and mechanical loading is important for
the strength development of this matrix. We therefore use a three‐dimensional (3D) culture …

Musculoskeletal soft tissues (eg, cartilage, tendon, ligament, skeletal muscle) are highly
organized and adapt to complex and distinct loadings they experience in vivo. The …

Tendons are composed of type I collagen fibrils and specialized extracellular matrix (ECM)
proteins that are hierarchically organized to transmit forces from muscle to bone. Reliable …

It is well known that cells can generate endogenous forces onto the extracellular matrix, but
to what extent the mechanical properties of the matrix influences these endogenous cellular …

Low temperature is a major plant stress factor that causes plant growth delay, stagnation,
and retrogression and reduces grain yield (Dolferus, 2014; Zhang et al., 2019). Over long …