Renin-angiotensin aldosterone system (RAAS) holds a crucial role in blood pressure
regulation. Aldosterone is encoded by the cytochrome 11B2 aldosterone synthase gene …

Objective. The aim of the present study was to clarify the endothelial function biomarkers
and carotid “intima media” thickness (IMT) changes in relation to GNB3 (rs5443) and NOS3 …

The mechanisms orchestrating the balance between nitric oxide and endothelium-derived
contracting factors, and genetic predisposition to endothelial dysfunction in hypertensive …

The cytochrome 11B2 aldosterone synthase gene (CYP11B2) one of the possible encoding
genes that relates to changes of aldosterone and blood pressure regulation. The aim is to …

This study aims to evaluate polymorphic variants of AGT (rs4762) and GNB3 (rs5443) genes
as predictors of myocardium left ventricular hypertrophy (LVH) in patients with essential …

Non-alcoholic fatty liver disease (NAFLD) is a pathology characterized by accumulation of
fat (steatosis) found in at least 5% of hepatocytes, and is a multifactorial disease including a …

The vascular endothelium is one of the earliest damage-targeted hypertensive-mediated
organs. The study aims to analyze the link of metabolic disorders with endothelial …

Objective: to evaluate the association of essential arterial hypertension (EAH) and its
severity with genes polymorphism of NOS3 (rs2070744) and GNB3 (rs5443) in West …

Introduction. Osteoarthritis (OA) is a multifactorial disorder in which ageing, genetic,
hormonal and mechanical factors are major contributors to its onset and progression …

Introduction. Rheumatoid arthritis (RA) is a multifactorial disease with genetic factors
involvement. Objective: to evaluate the alleles and genotypes frequency of eNOS gene T …