Integrins are heterodimeric transmembrane cell adhesion molecules made up of alpha (α)
and beta (β) subunits arranged in numerous dimeric pairings. These complexes have …

Cell migration is central to a multitude of physiological processes, including embryonic
development, immune surveillance, and wound healing, and deregulated migration is key to …

In their roles as major adhesion receptors, integrins signal across the plasma membrane in
both directions. Recent structural and cell biological data suggest models for how integrins …

The poster shows the major integrinligand combinations, using hypothetical cell surfaces.
We have not attempted a comprehensive cataloguing, but instead we have consulted with a …

Now available in a thoroughly revised Twelfth Edition, Wintrobe's Clinical Hematology
continues to be an industry leader with its ability to correlate basic science with the clinical …

The process of bone formation, remodelling and healing involves a coordinated action of
various cell types. Advances in understanding the biology of osteoblast cells during these …

Integrins are cell surface transmembrane receptors that recognize and bind to extracellular
matrix proteins and counter receptors. Binding of activated integrins to their ligands induces …

At implantation, with the acquisition of a receptive phenotype in the uterine epithelium, an
initial tenuous attachment of embryonic trophectoderm initiates reorganisation of epithelial …

Cell‐surface receptors acquire information from the extracellular environment and
coordinate intracellular responses. Many receptors do not operate as individual entities, but …

Cell adhesion mediated by integrin receptors has a critical function in organizing cells in
tissues and in guiding haematopoietic cells to their sites of action. However, integrin …