Calreticulin in phagocytosis and cancer: opposite roles in immune response outcomes

A Schcolnik-Cabrera, B Oldak, M Juárez… - Apoptosis, 2019 - Springer
Calreticulin (CRT) is a pleiotropic and highly conserved molecule that is mainly localized in
the endoplasmic reticulum. Recently, CRT has gained special interest for its functions …

Macrophage frequency in the bone marrow correlates with morphologic subtype of myeloproliferative neoplasm

DCA Molitor, P Boor, A Buness, RK Schneider… - Annals of …, 2021 - Springer
Bone marrow (BM) fibrosis in myeloproliferative neoplasms (MPNs) is associated with a
poor prognosis. The development of myelofibrosis and differentiation of mesenchymal …

Effects of repeated oral doses of ketoconazole on a sequential ascending single oral dose of fedratinib in healthy subjects

K Ogasawara, C Xu, V Kanamaluru… - Cancer Chemotherapy …, 2020 - Springer
Purpose Fedratinib is an orally administered Janus kinase 2-selective inhibitor that is
indicated for the treatment of adult patients with intermediate-2 or high-risk myelofibrosis in …

Assessment of effects of repeated oral doses of fedratinib on inhibition of cytochrome P450 activities in patients with solid tumors using a cocktail approach

K Ogasawara, PM LoRusso, AJ Olszanski… - Cancer Chemotherapy …, 2020 - Springer
Purpose Fedratinib, an oral selective kinase inhibitor with activity against both wild type and
mutationally activated Janus kinase 2, has been approved for the treatment of adult patients …

In-silico analysis: common biomarkers of NDs

D Sarkar, S Chakraborty, S Bhowmick, T Maiti - bioRxiv, 2021 - biorxiv.org
Neurodegenerative disorders (NDs) are a class of rapidly rising devastating diseases and
the reason behind are might be an improper function of related genes or a mutation in a …